5IC5
 
 | | Bacteriophytochrome response regulator RtBRR | | 分子名称: | CACODYLATE ION, Candidate response regulator, CheY, ... | | 著者 | Baker, A.W, Satyshur, K.A, Forest, K.T. | | 登録日 | 2016-02-22 | | 公開日 | 2016-03-02 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Arm-in-Arm Response Regulator Dimers Promote Intermolecular Signal Transduction.
J.Bacteriol., 198, 2016
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4XE0
 | | Idelalisib bound to the p110 subunit of PI3K delta | | 分子名称: | 5-fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4(3H)-one, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | | 著者 | Somoza, J.R, Villasenor, A. | | 登録日 | 2014-12-20 | | 公開日 | 2015-02-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.434 Å) | | 主引用文献 | Structural, Biochemical, and Biophysical Characterization of Idelalisib Binding to Phosphoinositide 3-Kinase delta.
J.Biol.Chem., 290, 2015
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5LTQ
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6XKZ
 | | R. capsulatus CIII2CIV tripartite super-complex, conformation B (SC-1B) | | 分子名称: | COPPER (II) ION, Cbb3-type cytochrome c oxidase subunit CcoP,Cytochrome c-type cyt cy, Cytochrome b, ... | | 著者 | Steimle, S, Van Eeuwen, T, Ozturk, Y, Kim, H.J, Braitbard, M, Selamoglu, N, Garcia, B.A, Schneidman-Duhovny, D, Murakami, K, Daldal, F. | | 登録日 | 2020-06-27 | | 公開日 | 2020-12-30 | | 最終更新日 | 2021-03-03 | | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | | 主引用文献 | Cryo-EM structures of engineered active bc 1 -cbb 3 type CIII 2 CIV super-complexes and electronic communication between the complexes.
Nat Commun, 12, 2021
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6IEQ
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3LIX
 | | crystal structure of htlv protease complexed with the inhibitor KNI-10729 | | 分子名称: | N-{(1S,2S)-1-benzyl-3-[(4R)-5,5-dimethyl-4-{[(1R)-1,2,2-trimethylpropyl]carbamoyl}-1,3-thiazolidin-3-yl]-2-hydroxy-3-oxopropyl}-3-methyl-N~2~-{(2S)-2-[(morpholin-4-ylacetyl)amino]-2-phenylacetyl}-L-valinamide, Protease, ZINC ION | | 著者 | Satoh, T, Li, M, Nguyen, J, Kiso, Y, Wlodawer, A, Gustchina, A. | | 登録日 | 2010-01-25 | | 公開日 | 2010-07-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease.
J.Mol.Biol., 401, 2010
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6L9Z
 | | 338 bp di-nucleosome assembled with linker histone H1.X | | 分子名称: | CALCIUM ION, CHLORIDE ION, DNA (338-MER), ... | | 著者 | Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A. | | 登録日 | 2019-11-11 | | 公開日 | 2021-02-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Engineering nucleosomes for generating diverse chromatin assemblies.
Nucleic Acids Res., 49, 2021
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6LAB
 | | 169 bp nucleosome, harboring cohesive DNA termini, assembled with linker histone H1.0 | | 分子名称: | CALCIUM ION, CHLORIDE ION, DNA (169-MER), ... | | 著者 | Adhireksan, Z, Sharma, D, Bao, Q, Lee, P.L, Padavattan, S, Davey, C.A. | | 登録日 | 2019-11-12 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Engineering nucleosomes for generating diverse chromatin assemblies.
Nucleic Acids Res., 49, 2021
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5LWD
 | | Thermolysin in complex with inhibitor (JC96) | | 分子名称: | CALCIUM ION, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Krimmer, S.G, Cramer, J, Heine, A, Klebe, G. | | 登録日 | 2016-09-15 | | 公開日 | 2016-12-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | | 主引用文献 | Elucidating the Origin of Long Residence Time Binding for Inhibitors of the Metalloprotease Thermolysin.
ACS Chem. Biol., 12, 2017
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7LRH
 | | C-terminal domain of RibD from Brucella abortus (5-amino-6-ribosylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate reductase) | | 分子名称: | Riboflavin biosynthesis protein RibD, SULFATE ION | | 著者 | Bonomi, H.R, Cerutti, M.L, Posadas, D.M, Goldbaum, F.A, Klinke, S. | | 登録日 | 2021-02-16 | | 公開日 | 2022-03-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | C-terminal domain of RibD from Brucella abortus (5-amino-6-ribosylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate reductase)
To be published
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6LA2
 | | 343 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0 | | 分子名称: | DNA (343-MER), Histone H1.0, Histone H2A type 1-B/E, ... | | 著者 | Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A. | | 登録日 | 2019-11-11 | | 公開日 | 2021-02-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.89 Å) | | 主引用文献 | Engineering nucleosomes for generating diverse chromatin assemblies.
Nucleic Acids Res., 49, 2021
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3LJA
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5IE1
 | | Crystal structure of BACE1 in complex with 3-(2-amino-6-(o-tolyl)quinolin-3-yl)-N-(3,3-dimethylbutyl)propanamide | | 分子名称: | 3-[2-amino-6-(2-methylphenyl)quinolin-3-yl]-N-(3,3-dimethylbutyl)propanamide, Beta-secretase 1, GLYCEROL, ... | | 著者 | Jordan, J.B, Whittington, D.A, Bartberger, M.D, Sickmier, E.A, Chen, K, Cheng, Y, Judd, T. | | 登録日 | 2016-02-24 | | 公開日 | 2016-03-30 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | | 主引用文献 | Fragment-Linking Approach Using (19)F NMR Spectroscopy To Obtain Highly Potent and Selective Inhibitors of beta-Secretase.
J.Med.Chem., 59, 2016
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6E53
 | | Structure of TERT in complex with a novel telomerase inhibitor | | 分子名称: | MAGNESIUM ION, RNA/DNA hairpin, Telomerase reverse transcriptase, ... | | 著者 | Hernandez-Sanchez, W, Huang, W, Plucinsky, B, Garcia-Vazquez, N, Berdis, A.J, Skordalakes, E, Taylor, D.J. | | 登録日 | 2018-07-19 | | 公開日 | 2019-03-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity.
Plos Biol., 17, 2019
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5ICU
 | | The crystal structure of CopC from Methylosinus trichosporium OB3b | | 分子名称: | CHLORIDE ION, COPPER (II) ION, CopC, ... | | 著者 | Lawton, T.J, Hurley, J.D, Rosenzweig, A.C. | | 登録日 | 2016-02-23 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | The CopC Family: Structural and Bioinformatic Insights into a Diverse Group of Periplasmic Copper Binding Proteins.
Biochemistry, 55, 2016
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6E5E
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3LKN
 | | Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 1918 strain | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... | | 著者 | Gras, S, Kedzierski, L, Valkenburg, S.A, Liu, Y.C, Denholm, J, Richards, M, Rimmelzwaan, G.F, Doherty, P.C, Turner, S.J, Rossjohn, J, Kedzierska, K. | | 登録日 | 2010-01-27 | | 公開日 | 2010-07-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses.
Proc.Natl.Acad.Sci.USA, 107, 2010
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8DVU
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4EU7
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1AIX
 | | HUMAN ALPHA-THROMBIN TERNARY COMPLEX WITH EXOSITE INHIBITOR HIRUGEN AND ACTIVE SITE INHIBITOR PHCH2OCO-D-DPA-PRO-BOROVAL | | 分子名称: | ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUGEN, ... | | 著者 | Skordalakes, E, Dodson, G, Elgendy, S, Goodwin, C.A, Green, D, Tyrrel, R, Scully, M.F, Freyssinet, J, Kakkar, V.V, Deadman, J. | | 登録日 | 1997-04-30 | | 公開日 | 1997-10-15 | | 最終更新日 | 2013-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships.
Protein Sci., 1, 1992
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6E5Q
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5LOL
 | | Glutathione-bound Dehydroascorbate Reductase 2 of Arabidopsis thaliana | | 分子名称: | GLUTATHIONE, GLYCEROL, Glutathione S-transferase DHAR2, ... | | 著者 | Young, D.R, Pallo, A, Bodra, N, Messens, J. | | 登録日 | 2016-08-09 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Arabidopsis thaliana dehydroascorbate reductase 2: Conformational flexibility during catalysis.
Sci Rep, 7, 2017
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5EZ9
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6LER
 | | 169 bp nucleosome harboring non-identical cohesive DNA termini. | | 分子名称: | CALCIUM ION, DNA (169-MER), Histone H2A type 1-B/E, ... | | 著者 | Sharma, D, Adhireksan, Z, Lee, P.L, Davey, C.A. | | 登録日 | 2019-11-26 | | 公開日 | 2021-03-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Engineering nucleosomes for generating diverse chromatin assemblies.
Nucleic Acids Res., 49, 2021
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6E5Y
 | | 1.50 Angstrom Resolution Crystal Structure of Argininosuccinate Synthase from Bordetella pertussis in Complex with AMP. | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Argininosuccinate synthase, ... | | 著者 | Minasov, G, Shuvalova, L, Dubrovska, I, Cardona-Correa, A, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2018-07-23 | | 公開日 | 2018-08-01 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | 1.50 Angstrom Resolution Crystal Structure of Argininosuccinate Synthase from Bordetella pertussis in Complex with AMP.
To Be Published
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