3LIX

crystal structure of htlv protease complexed with the inhibitor KNI-10729

Summary for 3LIX

Entry DOI	10.2210/pdb3lix/pdb
Related	2B7F 3LIN 3LIQ 3LIT 3LIV 3LIY
Related PRD ID	PRD_000581
Descriptor	Protease, ZINC ION, N-{(1S,2S)-1-benzyl-3-[(4R)-5,5-dimethyl-4-{[(1R)-1,2,2-trimethylpropyl]carbamoyl}-1,3-thiazolidin-3-yl]-2-hydroxy-3-oxopropyl}-3-methyl-N~2~-{(2S)-2-[(morpholin-4-ylacetyl)amino]-2-phenylacetyl}-L-valinamide, ... (4 entities in total)
Functional Keywords	hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Human T-lymphotropic virus 1
Total number of polymer chains	2
Total formula weight	25993.61
Authors	Satoh, T.,Li, M.,Nguyen, J.,Kiso, Y.,Wlodawer, A.,Gustchina, A. (deposition date: 2010-01-25, release date: 2010-07-14, Last modification date: 2023-09-06)
Primary citation	Satoh, T.,Li, M.,Nguyen, J.T.,Kiso, Y.,Gustchina, A.,Wlodawer, A. Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease. J.Mol.Biol., 401:626-641, 2010 Cited by PubMed: 20600105 DOI: 10.1016/j.jmb.2010.06.052 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation