3LIX
crystal structure of htlv protease complexed with the inhibitor KNI-10729
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protease | polymer | 116 | 12566.6 | 2 | UniProt (Q82134) Pfam (PF00077) | Human T-lymphotropic virus 1 | |
| 2 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | D (B) | N-{(1S,2S)-1-benzyl-3-[(4R)-5,5-dimethyl-4-{[(1R)-1,2,2-trimethylpropyl]carbamoyl}-1,3-thiazolidin-3-yl]-2-hydroxy-3-oxopropyl}-3-methyl-N~2~-{(2S)-2-[(morpholin-4-ylacetyl)amino]-2-phenylacetyl}-L-valinamide | non-polymer | 795.0 | 1 | BIRD (PRD_000581) Chemie (E17) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 116 (UniProt: Q82134)
| PDB | External Database | Details |
|---|---|---|
| Ile 40 | Leu 40 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25133.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 860.5 | |
| All* | Total formula weight | 25993.6 |
