5LWD

Thermolysin in complex with inhibitor (JC96)

Summary for 5LWD

Entry DOI	10.2210/pdb5lwd/pdb
Descriptor	Thermolysin, ZINC ION, CALCIUM ION, ... (7 entities in total)
Functional Keywords	hydrolase, metalloprotease, hydrolase inhibitor complex
Biological source	Bacillus thermoproteolyticus
Cellular location	Secreted: P00800
Total number of polymer chains	1
Total formula weight	35475.14
Authors	Krimmer, S.G.,Cramer, J.,Heine, A.,Klebe, G. (deposition date: 2016-09-15, release date: 2016-12-21, Last modification date: 2024-01-17)
Primary citation	Cramer, J.,Krimmer, S.G.,Fridh, V.,Wulsdorf, T.,Karlsson, R.,Heine, A.,Klebe, G. Elucidating the Origin of Long Residence Time Binding for Inhibitors of the Metalloprotease Thermolysin. ACS Chem. Biol., 12:225-233, 2017 Cited by PubMed: 27959500 DOI: 10.1021/acschembio.6b00979 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.23 Å)

Structure validation