5M05
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![BU of 5m05 by Molmil](/molmil-images/mine/5m05) | Chicken smooth muscle myosin motor domain co-crystallized with the specific CK-571 inhibitor, MgADP form | 分子名称: | 4-{[(2-chloro-3-fluorobenzyl)carbamoyl](methyl)amino}-3,4-dideoxy-5-O-(isoquinolin-3-ylcarbamoyl)-D-erythro-pentitol, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Sirigu, S, Hartman, J, Houdusse, A. | 登録日 | 2016-10-03 | 公開日 | 2016-11-16 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.675 Å) | 主引用文献 | Highly selective inhibition of myosin motors provides the basis of potential therapeutic application. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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8C8Q
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![BU of 8c8q by Molmil](/molmil-images/mine/8c8q) | Cytochrome c oxidase from Schizosaccharomyces pombe | 分子名称: | CALCIUM ION, COPPER (II) ION, Cytochrome c oxidase polypeptide 5, ... | 著者 | Moe, A, Adelroth, P, Brzezinski, P, Nasvik Ojemyr, L. | 登録日 | 2023-01-20 | 公開日 | 2023-03-01 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | Cryo-EM structure and function of S. pombe complex IV with bound respiratory supercomplex factor. Commun Chem, 6, 2023
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6ET7
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8OLR
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![BU of 8olr by Molmil](/molmil-images/mine/8olr) | Structure of yeast 20S proteasome in complex with the natural product beta-lactone inhibitor Cystargolide A | 分子名称: | CHLORIDE ION, Cystargolide A (bound), MAGNESIUM ION, ... | 著者 | Illigmann, A, Vielberg, M.-T, Lakemeyer, M, Wolf, F, Staudt, N, Dema, T, Stange, P, Malik, I, Grond, S, Sieber, S.A, Groll, M, Kaysser, L, Broetz-Oesterhelt, H. | 登録日 | 2023-03-30 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of Staphylococcus aureus ClpP Bound to the Covalent Active-Site Inhibitor Cystargolide A. Angew.Chem.Int.Ed.Engl., 63, 2024
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6XNT
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![BU of 6xnt by Molmil](/molmil-images/mine/6xnt) | Crystal structure of I91A mutant of human CEACAM1 | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, octyl beta-D-glucopyranoside | 著者 | Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S. | 登録日 | 2020-07-04 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium. Commun Biol, 4, 2021
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6RVV
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![BU of 6rvv by Molmil](/molmil-images/mine/6rvv) | Structure of left-handed protein cage consisting of 24 eleven-membered ring proteins held together by gold (I) bridges. | 分子名称: | GOLD ION, Transcription attenuation protein MtrB | 著者 | Malay, A.D, Miyazaki, N, Biela, A.P, Iwasaki, K, Heddle, J.G. | 登録日 | 2019-06-03 | 公開日 | 2019-06-12 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | An ultra-stable gold-coordinated protein cage displaying reversible assembly. Nature, 569, 2019
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6RZ0
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5LZ5
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![BU of 5lz5 by Molmil](/molmil-images/mine/5lz5) | Fragment-based inhibitors of Lipoprotein associated Phospholipase A2 | 分子名称: | 2-fluoranyl-5-[2-[(4~{S})-4-methyl-2-oxidanylidene-4-phenyl-pyrrolidin-1-yl]ethoxy]benzenecarbonitrile, CHLORIDE ION, Platelet-activating factor acetylhydrolase | 著者 | Woolford, A.J.A, Day, P.J. | 登録日 | 2016-09-29 | 公開日 | 2016-12-21 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2). J. Med. Chem., 59, 2016
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6XNW
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![BU of 6xnw by Molmil](/molmil-images/mine/6xnw) | Crystal structure of V39A mutant of human CEACAM1 | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, NICKEL (II) ION | 著者 | Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S. | 登録日 | 2020-07-04 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium. Commun Biol, 4, 2021
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6X90
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5M0B
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8CIK
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![BU of 8cik by Molmil](/molmil-images/mine/8cik) | Altai wapiti (Cervus elaphus sibiricus) chymosin at 2.2 A resolution | 分子名称: | Chymosin, GLYCEROL | 著者 | Diusenova, S.E, Shevtsov, M.B, Borshchevskiy, V.I, Belenkaya, S.V, Kolybalov, D.S, Arkhipov, S.G, Volosnikova, E.A, Elchaninov, V.V, Shcherbakov, D.N. | 登録日 | 2023-02-09 | 公開日 | 2023-03-08 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Altai wapiti (Cervus elaphus sibiricus) chymosin at 2.2 A resolution To Be Published
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8OLL
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![BU of 8oll by Molmil](/molmil-images/mine/8oll) | Staphylococcus aureus ClpP in complex with the natural product beta-lactone inhibitor Cystargolide A at 2.7 A resolution | 分子名称: | ATP-dependent Clp protease proteolytic subunit, Cystargolide A (bound) | 著者 | Illigmann, A, Vielberg, M.-T, Lakemeyer, M, Wolf, F, Staudt, N, Dema, T, Stange, P, Malik, I, Grond, S, Sieber, S.A, Groll, M, Kaysser, L, Broetz-Oesterhelt, H. | 登録日 | 2023-03-30 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of Staphylococcus aureus ClpP Bound to the Covalent Active-Site Inhibitor Cystargolide A. Angew.Chem.Int.Ed.Engl., 63, 2024
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8C3F
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![BU of 8c3f by Molmil](/molmil-images/mine/8c3f) | Double mutant I(L177)H/F(M197)H structure of Photosynthetic Reaction Center From Cereibacter sphaeroides strain RV | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | 著者 | Gabdulkhakov, A.G, Selikhanov, G.K, Fufina, T.Y, Vasilieva, L.G. | 登録日 | 2022-12-23 | 公開日 | 2023-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Properties and Crystal Structure of the Cereibacter sphaeroides Photosynthetic Reaction Center with Double Amino Acid Substitution I(L177)H + F(M197)H. Membranes (Basel), 13, 2023
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6XO1
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![BU of 6xo1 by Molmil](/molmil-images/mine/6xo1) | Crystal structure of N97A mutant of human CEACAM1 | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, MALONIC ACID | 著者 | Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S. | 登録日 | 2020-07-05 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.758 Å) | 主引用文献 | Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium. Commun Biol, 4, 2021
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8F0U
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![BU of 8f0u by Molmil](/molmil-images/mine/8f0u) | Structure of a 12mer DegP cage bound to the client protein hTRF1 | 分子名称: | Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1 | 著者 | Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E. | 登録日 | 2022-11-04 | 公開日 | 2022-11-23 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP. J.Am.Chem.Soc., 145, 2023
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6XNO
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![BU of 6xno by Molmil](/molmil-images/mine/6xno) | Crystal structure of E99A mutant of human CEACAM1 | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, MALONIC ACID, octyl beta-D-glucopyranoside | 著者 | Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S. | 登録日 | 2020-07-03 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium. Commun Biol, 4, 2021
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6UY5
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5M1Q
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![BU of 5m1q by Molmil](/molmil-images/mine/5m1q) | Crystal structure of the large terminase nuclease from thermophilic phage G20c with bound Zinc | 分子名称: | Phage terminase large subunit, ZINC ION | 著者 | Xu, R.G, Jenkins, H.T, Chechik, M, Blagova, E.V, Greive, S.J, Antson, A.A. | 登録日 | 2016-10-09 | 公開日 | 2016-10-26 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism. Nucleic Acids Res., 45, 2017
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8F26
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![BU of 8f26 by Molmil](/molmil-images/mine/8f26) | Structure of a 60mer DegP cage bound to the client protein hTRF1 | 分子名称: | Periplasmic serine endoprotease DegP, Telomeric repeat-binding factor 1 | 著者 | Harkness, R.W, Ripstein, Z.A, Di Trani, J.M, Kay, L.E. | 登録日 | 2022-11-07 | 公開日 | 2022-11-23 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (9.7 Å) | 主引用文献 | Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP. J.Am.Chem.Soc., 145, 2023
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7PU7
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![BU of 7pu7 by Molmil](/molmil-images/mine/7pu7) | DNA polymerase from M. tuberculosis | 分子名称: | DNA polymerase III subunit alpha, Template, ZINC ION, ... | 著者 | Borsellini, A, Lamers, M.H. | 登録日 | 2021-09-28 | 公開日 | 2022-02-23 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | DNA-Dependent Binding of Nargenicin to DnaE1 Inhibits Replication in Mycobacterium tuberculosis. Acs Infect Dis., 8, 2022
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6RFE
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![BU of 6rfe by Molmil](/molmil-images/mine/6rfe) | Human protein kinase CK2 alpha in complex with 2-cyano-2-propenamide compound 4 | 分子名称: | (~{E})-~{N}-(5-bromanyl-1,3,4-thiadiazol-2-yl)-2-cyano-3-(3-methoxy-4-oxidanyl-phenyl)prop-2-enamide, 1,2-ETHANEDIOL, Casein kinase II subunit alpha, ... | 著者 | Dalle Vedove, A, Zanforlin, E, Ribaudo, G, Zagotto, G, Battistutta, R, Lolli, G. | 登録日 | 2019-04-13 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | A novel class of selective CK2 inhibitors targeting its open hinge conformation. Eur.J.Med.Chem., 195, 2020
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8GA7
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4XTA
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8T1H
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