7PU7

DNA polymerase from M. tuberculosis

Summary for 7PU7

• Entry DOI: 10.2210/pdb7pu7/pdb
• EMDB information: 13654
• Descriptor: DNA polymerase III subunit alpha, Template, primer, ... (6 entities in total)
• Functional Keywords: inhibitor, dna polymerase, replication
• Biological source: Mycobacterium tuberculosis; More
• Total number of polymer chains: 3
• Total formula weight: 140334.19

Authors

Borsellini, A.,Lamers, M.H. (deposition date: 2021-09-28, release date: 2022-02-23, Last modification date: 2022-04-13)

• Primary citation: Chengalroyen, M.D.,Mason, M.K.,Borsellini, A.,Tassoni, R.,Abrahams, G.L.,Lynch, S.,Ahn, Y.M.,Ambler, J.,Young, K.,Crowley, B.M.,Olsen, D.B.,Warner, D.F.,Barry Iii, C.E.,Boshoff, H.I.M.,Lamers, M.H.,Mizrahi, V.; DNA-Dependent Binding of Nargenicin to DnaE1 Inhibits Replication in Mycobacterium tuberculosis.; Acs Infect Dis., 8:612-625, 2022; PubMed: 35143160; DOI: 10.1021/acsinfecdis.1c00643

Experimental method

ELECTRON MICROSCOPY (2.9 Å)