7PU7
DNA polymerase from M. tuberculosis
Summary for 7PU7
Entry DOI | 10.2210/pdb7pu7/pdb |
EMDB information | 13654 |
Descriptor | DNA polymerase III subunit alpha, Template, primer, ... (6 entities in total) |
Functional Keywords | inhibitor, dna polymerase, replication |
Biological source | Mycobacterium tuberculosis More |
Total number of polymer chains | 3 |
Total formula weight | 140334.19 |
Authors | Borsellini, A.,Lamers, M.H. (deposition date: 2021-09-28, release date: 2022-02-23, Last modification date: 2024-07-17) |
Primary citation | Chengalroyen, M.D.,Mason, M.K.,Borsellini, A.,Tassoni, R.,Abrahams, G.L.,Lynch, S.,Ahn, Y.M.,Ambler, J.,Young, K.,Crowley, B.M.,Olsen, D.B.,Warner, D.F.,Barry Iii, C.E.,Boshoff, H.I.M.,Lamers, M.H.,Mizrahi, V. DNA-Dependent Binding of Nargenicin to DnaE1 Inhibits Replication in Mycobacterium tuberculosis. Acs Infect Dis., 8:612-625, 2022 Cited by PubMed: 35143160DOI: 10.1021/acsinfecdis.1c00643 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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