8T1H

Cryo-EM structure of a full-length, native Drp1 dimer

Summary for 8T1H

• Entry DOI: 10.2210/pdb8t1h/pdb
• EMDB information: 40967
• Descriptor: Dynamin-1-like protein (1 entity in total)
• Functional Keywords: dynamin-related protein 1, drp1, mitochondrial fission, gtpase, cytosolic protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 163968.19

Authors

Rochon, K.,Mears, J.A. (deposition date: 2023-06-02, release date: 2024-02-21, Last modification date: 2024-05-01)

• Primary citation: Rochon, K.,Bauer, B.L.,Roethler, N.A.,Buckley, Y.,Su, C.C.,Huang, W.,Ramachandran, R.,Stoll, M.S.K.,Yu, E.W.,Taylor, D.J.,Mears, J.A.; Structural basis for regulated assembly of the mitochondrial fission GTPase Drp1.; Nat Commun, 15:1328-1328, 2024; PubMed: 38351080; DOI: 10.1038/s41467-024-45524-4

Experimental method

ELECTRON MICROSCOPY (5.97 Å)