8ECA
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![BU of 8eca by Molmil](/molmil-images/mine/8eca) | Covalently stabilized triangular trimer derived from Abeta16-36 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ORN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ORN-CYS-ILE-ILE-SAR-CYS-MET | 著者 | Kreutzer, A.G, Yoo, S, Nowick, J.S. | 登録日 | 2022-09-01 | 公開日 | 2023-05-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Probing differences among A beta oligomers with two triangular trimers derived from A beta. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EBZ
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6OLT
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![BU of 6olt by Molmil](/molmil-images/mine/6olt) | Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabF, and C12-crypto Acyl Carrier Protein, AcpP | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 2, Acyl carrier protein, N-[2-(dodecanoylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide | 著者 | Mindrebo, J.T, Kim, W.E, Bartholow, T.G, Chen, A, Davis, T.D, La Clair, J, Burkart, M.D, Noel, J.P. | 登録日 | 2019-04-17 | 公開日 | 2020-04-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Gating mechanism of elongating beta-ketoacyl-ACP synthases. Nat Commun, 11, 2020
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6OM2
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8DQ2
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![BU of 8dq2 by Molmil](/molmil-images/mine/8dq2) | X-ray crystal structure of Hansschlegelia quercus lanmodulin (LanM) with lanthanum (III) bound at pH 7 | 分子名称: | CITRIC ACID, EF-hand domain-containing protein, LANTHANUM (III) ION, ... | 著者 | Jung, J.J, Lin, C.-Y, Boal, A.K. | 登録日 | 2022-07-18 | 公開日 | 2023-06-07 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Enhanced rare-earth separation with a metal-sensitive lanmodulin dimer. Nature, 618, 2023
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6ONR
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![BU of 6onr by Molmil](/molmil-images/mine/6onr) | Dehaloperoxidase B in complex with substrate 4-methyl-cresol | 分子名称: | 1,2-ETHANEDIOL, 2,4-dimethylphenol, DI(HYDROXYETHYL)ETHER, ... | 著者 | Ghiladi, R.A, de Serrano, V.S, Malewschik, T. | 登録日 | 2019-04-22 | 公開日 | 2019-09-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | The multifunctional globin dehaloperoxidase strikes again: Simultaneous peroxidase and peroxygenase mechanisms in the oxidation of EPA pollutants. Arch.Biochem.Biophys., 673, 2019
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6OO1
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![BU of 6oo1 by Molmil](/molmil-images/mine/6oo1) | Dehaloperoxidase B in complex with substrate o-cresol | 分子名称: | 1,2-ETHANEDIOL, Dehaloperoxidase B, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Ghiladi, R.A, de Serrano, V.S, Malewschik, T. | 登録日 | 2019-04-22 | 公開日 | 2020-07-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.602 Å) | 主引用文献 | The multifunctional globin dehaloperoxidase strikes again: Simultaneous peroxidase and peroxygenase mechanisms in the oxidation of EPA pollutants. Arch.Biochem.Biophys., 673, 2019
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8BHB
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![BU of 8bhb by Molmil](/molmil-images/mine/8bhb) | GABA-A receptor a5 homomer - a5V3 - RO154513 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-5, ethyl 8-[(azanylidene-$l^{4}-azanylidene)amino]-5-methyl-6-oxidanylidene-4~{H}-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate | 著者 | Miller, P.S, Malinauskas, T.M, Hardwick, S.W, Chirgadze, D.Y, Wahid, A.A. | 登録日 | 2022-10-30 | 公開日 | 2023-11-01 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | 主引用文献 | The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors. Nat.Struct.Mol.Biol., 30, 2023
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6M9T
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![BU of 6m9t by Molmil](/molmil-images/mine/6m9t) | Crystal structure of EP3 receptor bound to misoprostol-FA | 分子名称: | (11alpha,12alpha,13E,16S)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, OLEIC ACID, ... | 著者 | Audet, M, White, K.L, Breton, B, Zarzycka, B, Han, G.W, Lu, Y, Gati, C, Batyuk, A, Popov, P, Velasquez, J, Manahan, D, Hu, H, Weierstall, U, Liu, W, Shui, W, Katrich, V, Cherezov, V, Hanson, M.A, Stevens, R.C. | 登録日 | 2018-08-24 | 公開日 | 2018-12-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of misoprostol bound to the labor inducer prostaglandin E2receptor. Nat. Chem. Biol., 15, 2019
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8BHG
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![BU of 8bhg by Molmil](/molmil-images/mine/8bhg) | GABA-A receptor a5 heteromer - a5V2 - Bretazenil | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bretazenil, DECYL-BETA-D-MALTOPYRANOSIDE, ... | 著者 | Miller, P.S, Malinauskas, T.M, Omari, K.E, Aricescu, A.R. | 登録日 | 2022-10-31 | 公開日 | 2023-11-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors. Nat.Struct.Mol.Biol., 30, 2023
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8BGI
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![BU of 8bgi by Molmil](/molmil-images/mine/8bgi) | GABA-A receptor a5 homomer - a5V1 - Flumazenil | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-5, Pregnanolone, ... | 著者 | Miller, P.S, Malinauskas, T.M, Omari, K.E, Aricescu, A.R. | 登録日 | 2022-10-27 | 公開日 | 2023-11-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors. Nat.Struct.Mol.Biol., 30, 2023
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8E9A
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![BU of 8e9a by Molmil](/molmil-images/mine/8e9a) | Crystal structure of AsfvPolX in complex with 10-23 DNAzyme and Mg | 分子名称: | DNA/RNA (52-MER), MAGNESIUM ION, Repair DNA polymerase X, ... | 著者 | Cramer, E.R, Robart, A.R, Kaya, A.I. | 登録日 | 2022-08-26 | 公開日 | 2023-06-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Structure of a 10-23 deoxyribozyme exhibiting a homodimer conformation. Commun Chem, 6, 2023
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6ODC
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![BU of 6odc by Molmil](/molmil-images/mine/6odc) | Crystal structure of HDAC8 in complex with compound 30 | 分子名称: | (2E)-3-[2-(3-cyclopentyl-5,5-dimethyl-2-oxoimidazolidin-1-yl)phenyl]-N-hydroxyprop-2-enamide, 1,2-ETHANEDIOL, Histone deacetylase 8, ... | 著者 | Zheng, X, Conti, C, Caravella, J, Zablocki, M.-M, Bair, K, Barczak, N, Han, B, Lancia Jr, D, Liu, C, Martin, M, Ng, P.Y, Rudnitskaya, A, Thomason, J.J, Garcia-Dancey, R, Hardy, C, Lahdenranta, J, Leng, C, Li, P, Pardo, E, Saldahna, A, Tan, T, Toms, A.V, Yao, L, Zhang, C. | 登録日 | 2019-03-26 | 公開日 | 2020-04-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-based Discovery of Novel N-(E)-N-Hydroxy-3-(2-(2-oxoimidazolidin-1-yl)phenyl)acrylamides as Potent and Selective HDAC8 inhibitors To Be Published
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6OC7
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![BU of 6oc7 by Molmil](/molmil-images/mine/6oc7) | HMP42 Fab in complex with Protein G | 分子名称: | Heavy chain of HMP42 Fab, Immunoglobulin G-binding protein G, Light chain for HMP42 Fab | 著者 | Bernard, S.M, Wilson, I.A. | 登録日 | 2019-03-22 | 公開日 | 2020-02-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.296 Å) | 主引用文献 | A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Science, 366, 2019
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7A18
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![BU of 7a18 by Molmil](/molmil-images/mine/7a18) | 50S Deinococcus radiodurans ribosome bounded with mycinamicin IV | 分子名称: | 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, ... | 著者 | Breiner, E, Eyal, Z, Matzov, D, Halfon, Y, Cimicata, G, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A. | 登録日 | 2020-08-12 | 公開日 | 2021-10-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida. Nucleic Acids Res., 49, 2021
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6MFL
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![BU of 6mfl by Molmil](/molmil-images/mine/6mfl) | Structure of siderophore binding protein BauB bound to a complex between two molecules of acinetobactin and ferric iron. | 分子名称: | 1,2-ETHANEDIOL, FE (III) ION, Siderophore Binding Protein BauB, ... | 著者 | Gulick, A.M, Bailey, D.C, Wencewicz, T.A. | 登録日 | 2018-09-11 | 公開日 | 2018-11-21 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of the Siderophore Binding Protein BauB Bound to an Unusual 2:1 Complex Between Acinetobactin and Ferric Iron. Biochemistry, 57, 2018
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7A59
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![BU of 7a59 by Molmil](/molmil-images/mine/7a59) | Crimean-Congo Hemorrhagic Fever Virus Envelope Glycoprotein Gc W1191H/W1197A/W1199A Mutant in Postfusion Conformation (Orthorhombic Crystal Form) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Envelopment polyprotein, ... | 著者 | Hellert, J, Guardado-Calvo, P, Rey, F.A. | 登録日 | 2020-08-20 | 公開日 | 2021-10-06 | 最終更新日 | 2022-04-20 | 実験手法 | X-RAY DIFFRACTION (2.197 Å) | 主引用文献 | Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies. Science, 375, 2022
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7P5Q
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7A6Z
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![BU of 7a6z by Molmil](/molmil-images/mine/7a6z) | Structure of P226G BlaC from Mycobacterium tuberculosis | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase, GLYCEROL, ... | 著者 | Chikunova, A, Ahmad, M.U, Perrakis, A, Ubbink, M. | 登録日 | 2020-08-27 | 公開日 | 2021-10-06 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Conserved proline residues prevent dimerization and aggregation in the beta-lactamase BlaC. Protein Sci., 33, 2024
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6OJ2
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![BU of 6oj2 by Molmil](/molmil-images/mine/6oj2) | Crystal structure of tRNA^ Ala(GGC) bound to the near-cognate 70S A-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Nguyen, H.A, Sunita, S, Dunham, C.M. | 登録日 | 2019-04-10 | 公開日 | 2020-06-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Disruption of evolutionarily correlated tRNA elements impairs accurate decoding. Proc.Natl.Acad.Sci.USA, 117, 2020
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8DNT
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![BU of 8dnt by Molmil](/molmil-images/mine/8dnt) | SARS-CoV-2 specific T cell receptor | 分子名称: | Beta-2-microglobulin, MHC class I antigen alpha chain, Nucleoprotein, ... | 著者 | Gallagher, D.T, Wu, D, Gowthaman, R, Pierce, B.G, Mariuzza, R.A, Weng, N.P. | 登録日 | 2022-07-11 | 公開日 | 2023-07-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | 主引用文献 | SARS-CoV-2 infection establishes a stable and age-independent CD8 + T cell response against a dominant nucleocapsid epitope using restricted T cell receptors. Nat Commun, 14, 2023
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7P5S
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7P5G
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6O4B
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![BU of 6o4b by Molmil](/molmil-images/mine/6o4b) | Structure of ALDH7A1 mutant W175G complexed with NAD | 分子名称: | 1,2-ETHANEDIOL, Alpha-aminoadipic semialdehyde dehydrogenase, CHLORIDE ION, ... | 著者 | Tanner, J.J, Korasick, D.A, Laciak, A.R. | 登録日 | 2019-02-28 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural and biochemical consequences of pyridoxine-dependent epilepsy mutations that target the aldehyde binding site of aldehyde dehydrogenase ALDH7A1. Febs J., 287, 2020
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7PHP
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![BU of 7php by Molmil](/molmil-images/mine/7php) | Structure of Multidrug and Toxin Compound Extrusion (MATE) transporter NorM by NabFab-fiducial assisted cryo-EM | 分子名称: | Anti-Fab nanobody, Multidrug resistance protein NorM, NabFab HC, ... | 著者 | Bloch, J.S, Mukherjee, S, Kowal, J, Niederer, M, Pardon, E, Steyaert, J, Kossiakoff, A.A, Locher, K.P. | 登録日 | 2021-08-18 | 公開日 | 2021-09-01 | 最終更新日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins. Proc.Natl.Acad.Sci.USA, 118, 2021
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