8EBZ

Crystal Structure of GMPPNP-bound KRAS-G13D mutant at 1.2 Ang resolution

Summary for 8EBZ

Entry DOI	10.2210/pdb8ebz/pdb
Descriptor	Isoform 2B of GTPase KRas, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	kras, k-ras, mutant, cancer, oncoprotein, ras, small gtpase, gmppnp, gppnhp, g13d, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	20022.26
Authors	Chan, A.H.,Simanshu, D.K. (deposition date: 2022-08-31, release date: 2023-06-07, Last modification date: 2023-11-15)
Primary citation	Chao, F.A.,Chan, A.H.,Dharmaiah, S.,Schwieters, C.D.,Tran, T.H.,Taylor, T.,Ramakrishnan, N.,Esposito, D.,Nissley, D.V.,McCormick, F.,Simanshu, D.K.,Cornilescu, G. Reduced dynamic complexity allows structure elucidation of an excited state of KRAS G13D . Commun Biol, 6:594-594, 2023 Cited by PubMed: 37268708 DOI: 10.1038/s42003-023-04960-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation