8EBZ
Crystal Structure of GMPPNP-bound KRAS-G13D mutant at 1.2 Ang resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform 2B of GTPase KRas | polymer | 170 | 19402.8 | 1 | UniProt (P01116-2) Pfam (PF00071) UniProt (by SIFTS) (P01116) | Homo sapiens (human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | B (A) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 3 | C, D, E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | G (A) | water | water | 18.0 | 186 | Chemie (HOH) |
Sequence modifications
A: 1 - 169 (UniProt: P01116-2)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Asp 13 | Gly 13 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19402.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 619.4 | |
| All* | Total formula weight | 20022.3 |
