8BHG

GABA-A receptor a5 heteromer - a5V2 - Bretazenil

Summary for 8BHG

Entry DOI	10.2210/pdb8bhg/pdb
Descriptor	Gamma-aminobutyric acid receptor subunit alpha-5, Gamma-aminobutyric acid receptor subunit gamma-2, Bretazenil, ... (7 entities in total)
Functional Keywords	plgic gaba neurotransmission, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	210364.94
Authors	Miller, P.S.,Malinauskas, T.M.,Omari, K.E.,Aricescu, A.R. (deposition date: 2022-10-31, release date: 2023-11-15, Last modification date: 2023-12-27)
Primary citation	Kasaragod, V.B.,Malinauskas, T.,Wahid, A.A.,Lengyel, J.,Knoflach, F.,Hardwick, S.W.,Jones, C.F.,Chen, W.N.,Lucas, X.,El Omari, K.,Chirgadze, D.Y.,Aricescu, A.R.,Cecere, G.,Hernandez, M.C.,Miller, P.S. The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors. Nat.Struct.Mol.Biol., 30:1936-1946, 2023 Cited by PubMed: 37903907 DOI: 10.1038/s41594-023-01133-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.39 Å)

Structure validation