6O4B
Structure of ALDH7A1 mutant W175G complexed with NAD
Summary for 6O4B
Entry DOI | 10.2210/pdb6o4b/pdb |
Descriptor | Alpha-aminoadipic semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, CHLORIDE ION, ... (8 entities in total) |
Functional Keywords | aldehyde dehydrogenase, nad, oxidoreductase, lysine catabolism |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 8 |
Total formula weight | 453337.11 |
Authors | Tanner, J.J.,Korasick, D.A.,Laciak, A.R. (deposition date: 2019-02-28, release date: 2019-07-24, Last modification date: 2023-10-11) |
Primary citation | Laciak, A.R.,Korasick, D.A.,Wyatt, J.W.,Gates, K.S.,Tanner, J.J. Structural and biochemical consequences of pyridoxine-dependent epilepsy mutations that target the aldehyde binding site of aldehyde dehydrogenase ALDH7A1. Febs J., 287:173-189, 2020 Cited by PubMed: 31302938DOI: 10.1111/febs.14997 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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