7DJY
| Clec4f Nanobody 322 | Descriptor: | Clec4f Nanobody 322 | Authors: | Wen, Y, Zheng, F. | Deposit date: | 2020-11-22 | Release date: | 2021-11-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Clec4f Nanobody 322 To Be Published
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6YK0
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6YJZ
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6YK1
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3ICH
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3ICI
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6W07
| Bruton's tyrosine kinase in complex with compound 1 | Descriptor: | DIMETHYL SULFOXIDE, Tyrosine-protein kinase BTK, ~{N}-[[2-methyl-4-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]methyl]-3-propan-2-yloxy-azetidine-1-carboxamide | Authors: | Metrick, C.M, Marcotte, D.J. | Deposit date: | 2020-02-29 | Release date: | 2020-12-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Discovery of BIIB068: A Selective, Potent, Reversible Bruton's Tyrosine Kinase Inhibitor as an Orally Efficacious Agent for Autoimmune Diseases. J.Med.Chem., 63, 2020
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6VXQ
| Bruton's tyrosine kinase in complex with compound 5 | Descriptor: | DIMETHYL SULFOXIDE, N-{[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]methyl}benzamide, Tyrosine-protein kinase BTK | Authors: | Metrick, C.M, Marcotte, D.J. | Deposit date: | 2020-02-23 | Release date: | 2020-12-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Discovery of BIIB068: A Selective, Potent, Reversible Bruton's Tyrosine Kinase Inhibitor as an Orally Efficacious Agent for Autoimmune Diseases. J.Med.Chem., 63, 2020
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6W06
| Bruton's tyrosine kinase in complex with compound 6 | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-~{tert}-butyl-~{N}-[[4-(7~{H}-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]methyl]benzamide, DIMETHYL SULFOXIDE, ... | Authors: | Metrick, C.M, Marcotte, D.J. | Deposit date: | 2020-02-29 | Release date: | 2020-12-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Discovery of BIIB068: A Selective, Potent, Reversible Bruton's Tyrosine Kinase Inhibitor as an Orally Efficacious Agent for Autoimmune Diseases. J.Med.Chem., 63, 2020
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5IML
| Nanobody targeting human Vsig4 in Spacegroup P212121 | Descriptor: | Nanobody, V-set and immunoglobulin domain-containing protein 4 | Authors: | Wen, Y. | Deposit date: | 2016-03-06 | Release date: | 2017-01-11 | Last modified: | 2017-07-05 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity Immunobiology, 222, 2017
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5IMK
| Nanobody targeting human Vsig4 in Spacegroup C2 | Descriptor: | Nanobody, V-set and immunoglobulin domain-containing protein 4 | Authors: | Wen, Y. | Deposit date: | 2016-03-06 | Release date: | 2017-01-11 | Last modified: | 2017-07-05 | Method: | X-RAY DIFFRACTION (1.227 Å) | Cite: | Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity Immunobiology, 222, 2017
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8H3Y
| Bacteroide Fragilis Toxin in complex with nanobody 327 | Descriptor: | Fragilysin, Nanobody 327, ZINC ION | Authors: | Wen, Y, Guo, Y. | Deposit date: | 2022-10-09 | Release date: | 2023-02-08 | Last modified: | 2023-03-15 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Screening and epitope characterization of diagnostic nanobody against total and activated Bacteroides fragilis toxin. Front Immunol, 14, 2023
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8H3X
| Bacteroide Fragilis Toxin in complex with nanobody 282 | Descriptor: | Fragilysin, ZINC ION, nanobody 282 | Authors: | Wen, Y, Guo, Y. | Deposit date: | 2022-10-09 | Release date: | 2023-02-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Screening and epitope characterization of diagnostic nanobody against total and activated Bacteroides fragilis toxin. Front Immunol, 14, 2023
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8GRA
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5WWL
| Crystal structure of the Schizogenesis pombe kinetochore Mis12C subcomplex | Descriptor: | Centromere protein mis12, Kinetochore protein nnf1 | Authors: | Wang, C, Zhou, X, Wu, M, Zhang, X, Zang, J. | Deposit date: | 2017-01-02 | Release date: | 2017-11-15 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Phosphorylation of CENP-C by Aurora B facilitates kinetochore attachment error correction in mitosis. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4P08
| Engineered thermostable dimeric cocaine esterase | Descriptor: | Cocaine esterase | Authors: | Rodgers, D.W, Chow, K.-M, Fang, L, Zhan, C.-G. | Deposit date: | 2014-02-20 | Release date: | 2014-07-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.341 Å) | Cite: | Rational design, preparation, and characterization of a therapeutic enzyme mutant with improved stability and function for cocaine detoxification. Acs Chem.Biol., 9, 2014
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5X5L
| Crystal structure of response regulator AdeR DNA binding domain in complex with an intercistronic region | Descriptor: | AdeR, DNA (5'-D(P*TP*AP*AP*AP*GP*TP*GP*TP*GP*GP*AP*GP*TP*AP*AP*GP*TP*GP*TP*GP*GP*AP*GP*A)-3'), DNA (5'-D(P*TP*CP*TP*CP*CP*AP*CP*AP*CP*TP*TP*AP*CP*TP*CP*CP*AP*CP*AP*CP*TP*TP*TP*A)-3') | Authors: | Wen, Y. | Deposit date: | 2017-02-16 | Release date: | 2017-08-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Mechanistic insight into how multidrug resistant Acinetobacter baumannii response regulator AdeR recognizes an intercistronic region. Nucleic Acids Res., 45, 2017
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5X5J
| Crystal structure of response regulator AdeR receiver domain | Descriptor: | AdeR | Authors: | Wen, Y. | Deposit date: | 2017-02-16 | Release date: | 2017-08-30 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.401 Å) | Cite: | Mechanistic insight into how multidrug resistant Acinetobacter baumannii response regulator AdeR recognizes an intercistronic region. Nucleic Acids Res., 45, 2017
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5XJP
| Crystal structure of response regulator AdeR receiver domain with Mg | Descriptor: | AdeR, MAGNESIUM ION | Authors: | Wen, Y. | Deposit date: | 2017-05-03 | Release date: | 2017-08-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.597 Å) | Cite: | Mechanistic insight into how multidrug resistant Acinetobacter baumannii response regulator AdeR recognizes an intercistronic region. Nucleic Acids Res., 45, 2017
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5XP0
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6IS2
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6IS3
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6IS1
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6IS4
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6JJJ
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