5IML

Nanobody targeting human Vsig4 in Spacegroup P212121

Summary for 5IML

• Entry DOI: 10.2210/pdb5iml/pdb
• Related: 5IMK 5IMM 5IMO
• Descriptor: V-set and immunoglobulin domain-containing protein 4, Nanobody (3 entities in total)
• Functional Keywords: nanobody, complement receptor, vsig4 crig, immune system
• Biological source: Homo sapiens (Human); More
• Cellular location: Membrane ; Single-pass type I membrane protein : Q9Y279
• Total number of polymer chains: 2
• Total formula weight: 39205.79

Authors

Wen, Y. (deposition date: 2016-03-06, release date: 2017-01-11, Last modification date: 2017-07-05)

• Primary citation: Wen, Y.,Ouyang, Z.,Schoonooghe, S.,Luo, S.,De Baetselier, P.,Lu, W.,Muyldermans, S.,Raes, G.,Zheng, F.; Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity; Immunobiology, 222:807-813, 2017; PubMed: 27889311; DOI: 10.1016/j.imbio.2016.11.008

Experimental method

X-RAY DIFFRACTION (1.8 Å)