2B7V
 
 | | Structure of ADAR2 dsRBM2 | | Descriptor: | Double-stranded RNA-specific editase 1 | | Authors: | Stefl, R, Xu, M, Skrisovska, L, Emeson, R.B, Allain, F.H.-T. | | Deposit date: | 2005-10-05 | | Release date: | 2006-03-14 | | Last modified: | 2022-03-09 | | Method: | SOLUTION NMR | | Cite: | Structure and specific RNA binding of ADAR2 double-stranded RNA binding motifs.
Structure, 14, 2006
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6ISK
 | | SnoaL-like cyclase XimE | | Descriptor: | 1,2-ETHANEDIOL, MALONIC ACID, XimE, ... | | Authors: | He, B, Zhou, T, Bu, X, Weng, J, Xu, J, Lin, S, Zheng, J, Zhao, Y, Xu, M. | | Deposit date: | 2018-11-16 | | Release date: | 2019-11-20 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Enzymatic Pyran Formation Involved in Xiamenmycin Biosynthesis
Acs Catalysis, 9, 2019
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6ISL
 | | SnoaL-like cyclase XimE with its product xiamenmycin B | | Descriptor: | (2R,3S)-2-methyl-2-(4-methylpent-3-enyl)-3-oxidanyl-3,4-dihydrochromene-6-carboxylic acid, XimE, SnoaL-like domain protein | | Authors: | He, B, Zhou, T, Bu, X, Weng, J, Xu, J, Lin, S, Zheng, J, Zhao, Y, Xu, M. | | Deposit date: | 2018-11-16 | | Release date: | 2019-11-20 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Enzymatic Pyran Formation Involved in Xiamenmycin Biosynthesis
Acs Catalysis, 9, 2019
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4NOO
 | | Molecular mechanism for self-protection against type VI secretion system in Vibrio cholerae | | Descriptor: | Putative uncharacterized protein, VgrG protein | | Authors: | Yang, X, Xu, M, Jiang, T, Fan, Z. | | Deposit date: | 2013-11-20 | | Release date: | 2014-04-09 | | Last modified: | 2014-04-16 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Molecular mechanism for self-protection against the type VI secretion system in Vibrio cholerae.
Acta Crystallogr.,Sect.D, 70, 2014
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3V69
 | | Filia-N crystal structure | | Descriptor: | Protein Filia | | Authors: | Wang, J, Xu, M, Zhu, K, Li, L, Liu, X. | | Deposit date: | 2011-12-19 | | Release date: | 2012-02-15 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The N-terminus of FILIA Forms an Atypical KH Domain with a Unique Extension Involved in Interaction with RNA.
Plos One, 7, 2012
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5X3P
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5X4L
 | | Crystal structure of the UBX domain of human UBXD7 in complex with p97 N domain | | Descriptor: | Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 7 | | Authors: | Jiang, T, Li, Z, Wang, Y, Xu, M. | | Deposit date: | 2017-02-13 | | Release date: | 2017-03-22 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.402 Å) | | Cite: | Crystal structures of the UBX domain of human UBXD7 and its complex with p97 ATPase
Biochem. Biophys. Res. Commun., 486, 2017
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4GDF
 | | A Crystal Structure of SV40 Large T Antigen | | Descriptor: | DNA (32-MER), Large T antigen, ZINC ION | | Authors: | Chang, Y.P, Xu, M, Chen, X.S. | | Deposit date: | 2012-07-31 | | Release date: | 2013-04-10 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Mechanism of Origin DNA Recognition and Assembly of an Initiator-Helicase Complex by SV40 Large Tumor Antigen.
Cell Rep, 3, 2013
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3OLC
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5Y62
 | | YfiR complexed with GMP | | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, YfiR | | Authors: | Zhou, L, Xu, M, Jiang, T. | | Deposit date: | 2017-08-10 | | Release date: | 2017-09-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural insights into the functional role of GMP in modulating the YfiBNR system
Biochem. Biophys. Res. Commun., 493, 2017
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5Y61
 | | YfiB-YfiR complexed with GMP | | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, YfiB, YfiR | | Authors: | Zhou, L, Xu, M, Jiang, T. | | Deposit date: | 2017-08-10 | | Release date: | 2017-09-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | Structural insights into the functional role of GMP in modulating the YfiBNR system
Biochem. Biophys. Res. Commun., 493, 2017
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8HEH
 | | Crystal structure of GCN5-related N-acetyltransferase 05790 | | Descriptor: | COENZYME A, GLYCEROL, GNAT family N-acetyltransferase | | Authors: | Xu, M.X, Ran, T.T, Wang, W. | | Deposit date: | 2022-11-08 | | Release date: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal structure of prodigiosin binding protein PgbP, a GNAT family protein, in Serratia marcescens FS14.
Biochem.Biophys.Res.Commun., 640, 2022
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4TQN
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5XGL
 | | Co-crystal structure of Ac-AChBPP in complex with alpha-conotoxin LvIA | | Descriptor: | Alpha-conotoxin LvIA, Soluble acetylcholine receptor | | Authors: | Wang, X.Q, Xu, M.Y, Luo, S.L, Zhu, X.P. | | Deposit date: | 2017-04-14 | | Release date: | 2018-06-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.439 Å) | | Cite: | The crystal structure of Ac-AChBP in complex with alpha-conotoxin LvIA reveals the mechanism of its selectivity towards different nAChR subtypes
Protein Cell, 8, 2017
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1XJU
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1XJT
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8GK7
 | | MsbA bound to cerastecin C | | Descriptor: | 2-[(4-butylbenzene-1-sulfonyl)amino]-5-[(3-{4-[(4-butylbenzene-1-sulfonyl)amino]-3-carboxyanilino}-3-oxopropyl)carbamoyl]benzoic acid, Lipid A export ATP-binding/permease protein MsbA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Chen, Y, Klein, D. | | Deposit date: | 2023-03-17 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | Cerastecins inhibit membrane lipooligosaccharide transport in drug-resistant Acinetobacter baumannii
Nat Microbiol, 2024
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6XM2
 | | The structure of the 4A11.v7 antibody in complex with human TGFb2 | | Descriptor: | 4A11.v7 heavy chain Fab (VH-CH1) IgG1 humanized, 4A11.v7 kappa light chain Fab (VL-CL) humanized, Transforming growth factor beta-2 | | Authors: | Lupardus, P.J, Yin, J.P. | | Deposit date: | 2020-06-29 | | Release date: | 2021-07-07 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | TGF beta 2 and TGF beta 3 isoforms drive fibrotic disease pathogenesis.
Sci Transl Med, 13, 2021
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8UV0
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8E50
 | | Cryo-EM structure of human glycerol-3-phosphate acyltransferase 1 (GPAT1) in complex with CoA and palmitoyl-LPA | | Descriptor: | (2R)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate, COENZYME A, Glycerol-3-phosphate acyltransferase 1, ... | | Authors: | Wasilko, D.J, Johnson, Z.L, Ammirati, M, Chang, J.S, Han, S, Wu, H. | | Deposit date: | 2022-08-19 | | Release date: | 2022-12-21 | | Last modified: | 2023-02-01 | | Method: | ELECTRON MICROSCOPY (3.67 Å) | | Cite: | Structural basis of the acyl-transfer mechanism of human GPAT1.
Nat.Struct.Mol.Biol., 30, 2023
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8E4Y
 | | Cryo-EM structure of human glycerol-3-phosphate acyltransferase 1 (GPAT1) in complex with 2-oxohexadecyl-CoA | | Descriptor: | (2R)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate, Glycerol-3-phosphate acyltransferase 1, mitochondrial, ... | | Authors: | Johnson, Z.L, Wasilko, D.J, Ammirati, M, Chang, J.S, Han, S, Wu, H. | | Deposit date: | 2022-08-19 | | Release date: | 2022-12-21 | | Last modified: | 2023-02-01 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural basis of the acyl-transfer mechanism of human GPAT1.
Nat.Struct.Mol.Biol., 30, 2023
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7FCQ
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7FCP
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6U3Q
 | | The atomic structure of a human adeno-associated virus capsid isolate (AAVhu69/AAVv66) | | Descriptor: | Capsid protein VP1 | | Authors: | Hsu, H.-L, Brown, A, Loveland, A, Tai, P, Korostelev, A, Gao, G. | | Deposit date: | 2019-08-22 | | Release date: | 2020-05-27 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (2.46 Å) | | Cite: | Structural characterization of a novel human adeno-associated virus capsid with neurotropic properties.
Nat Commun, 11, 2020
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8DEG
 | | Crystal structure of DLK in complex with inhibitor DN0011197 | | Descriptor: | Mitogen-activated protein kinase kinase kinase 12, methyl (1S,4S)-5-{(4P)-4-[5-amino-6-(difluoromethoxy)pyrazin-2-yl]-6-[(1R,4R)-2-azabicyclo[2.1.1]hexan-2-yl]pyridin-2-yl}-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate | | Authors: | Srivastava, A, Lexa, K, de Vicente, J. | | Deposit date: | 2022-06-20 | | Release date: | 2022-12-14 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Discovery of Potent and Selective Dual Leucine Zipper Kinase/Leucine Zipper-Bearing Kinase Inhibitors with Neuroprotective Properties in In Vitro and In Vivo Models of Amyotrophic Lateral Sclerosis.
J.Med.Chem., 65, 2022
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