8GK7
MsbA bound to cerastecin C
Summary for 8GK7
Entry DOI | 10.2210/pdb8gk7/pdb |
EMDB information | 40180 |
Descriptor | Lipid A export ATP-binding/permease protein MsbA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 2-[(4-butylbenzene-1-sulfonyl)amino]-5-[(3-{4-[(4-butylbenzene-1-sulfonyl)amino]-3-carboxyanilino}-3-oxopropyl)carbamoyl]benzoic acid (3 entities in total) |
Functional Keywords | msba, antibacterial, inhibitor, cerastecin, antimicrobial protein |
Biological source | Acinetobacter baumannii |
Total number of polymer chains | 2 |
Total formula weight | 135578.44 |
Authors | |
Primary citation | Wang, H.,Ishchenko, A.,Skudlarek, J.,Shen, P.,Dzhekieva, L.,Painter, R.E.,Chen, Y.T.,Bukhtiyarova, M.,Leithead, A.,Tracy, R.,Babaoglu, K.,Bahnck-Teets, C.,Buevich, A.,Cabalu, T.D.,Labroli, M.,Lange, H.,Lei, Y.,Li, W.,Liu, J.,Mann, P.A.,Meng, T.,Mitchell, H.J.,Mulhearn, J.,Scapin, G.,Sha, D.,Shaw, A.W.,Si, Q.,Tong, L.,Wu, C.,Wu, Z.,Xiao, J.C.,Xu, M.,Zhang, L.K.,McKenney, D.,Miller, R.R.,Black, T.A.,Cooke, A.,Balibar, C.J.,Klein, D.J.,Raheem, I.,Walker, S.S. Cerastecins inhibit membrane lipooligosaccharide transport in drug-resistant Acinetobacter baumannii. Nat Microbiol, 9:1244-1255, 2024 Cited by PubMed: 38649414DOI: 10.1038/s41564-024-01667-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.32 Å) |
Structure validation
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