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6BZ9
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BU of 6bz9 by Molmil
Crystal structure of human caspase-1 in complex with Ac-FLTD-CMK
分子名称: Ac-FLTD-CMK, Caspase-1, DI(HYDROXYETHYL)ETHER
著者Xiao, T.S, Yang, J, Liu, Z, Wang, C, Yang, R.
登録日2017-12-22
公開日2018-06-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.796 Å)
主引用文献Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8T5Q
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BU of 8t5q by Molmil
SARS-CoV-2 ORF3a peptide in complex with TRAF2 TRAF domain
分子名称: DI(HYDROXYETHYL)ETHER, ORF3a protein, TETRAETHYLENE GLYCOL, ...
著者Busscher, B.M, Xiao, T.S.
登録日2023-06-14
公開日2023-11-29
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献SARS-CoV-2 ORF3a-Mediated NF-kappa B Activation Is Not Dependent on TRAF-Binding Sequence.
Viruses, 15, 2023
8T5P
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BU of 8t5p by Molmil
SARS-CoV-2 ORF3a peptide in complex with TRAF3 TRAF domain
分子名称: ORF3a protein, TNF receptor-associated factor 3
著者Busscher, B.M, Xiao, T.S.
登録日2023-06-14
公開日2023-11-29
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献SARS-CoV-2 ORF3a-Mediated NF-kappa B Activation Is Not Dependent on TRAF-Binding Sequence.
Viruses, 15, 2023
4QLC
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BU of 4qlc by Molmil
Crystal structure of chromatosome at 3.5 angstrom resolution
分子名称: CITRIC ACID, DNA (167-mer), H5, ...
著者Jiang, J.S, Zhou, B.R, Xiao, T.S, Bai, Y.W.
登録日2014-06-11
公開日2015-07-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.503 Å)
主引用文献Structural Mechanisms of Nucleosome Recognition by Linker Histones.
Mol.Cell, 33 Suppl 1, 2015
6UP4
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BU of 6up4 by Molmil
Crystal structure of the murine DHX36 helicase in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Dhx36 protein, MAGNESIUM ION
著者Liu, Z, Xiao, T.S.
登録日2019-10-16
公開日2020-04-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Function of Auxiliary Domains of the DEAH/RHA Helicase DHX36 in RNA Remodeling.
J.Mol.Biol., 432, 2020
6UP3
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BU of 6up3 by Molmil
Crystal structure of the murine DHX36 helicase in complex with ANP
分子名称: Dhx36 protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Chuenchor, W, Jiang, J, Xiao, T.S.
登録日2019-10-16
公開日2020-10-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.691 Å)
主引用文献Crystal structure of the murine DHX36 helicase in complex with ANP
To be published
6UP2
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BU of 6up2 by Molmil
Crystal structure of the murine DHX36 helicase
分子名称: CHLORIDE ION, Dhx36 protein, GLYCEROL
著者Chuenchor, W, Jiang, J, Xiao, T.S.
登録日2019-10-16
公開日2020-10-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Crystal structure of the murine DHX36 helicase
To be published
6VIE
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BU of 6vie by Molmil
Structure of caspase-1 in complex with gasdermin D
分子名称: Caspase-1 subunit p10, Caspase-1 subunit p20, Gasdermin-D
著者Liu, Z, Xiao, T.S.
登録日2020-01-13
公開日2020-07-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage.
Immunity, 53, 2020
6NRY
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BU of 6nry by Molmil
Crystal structure of human caspase-4
分子名称: Caspase-4, GLYCEROL
著者Yang, J, Liu, Z, Shi, W, Xiao, T.S.
登録日2019-01-24
公開日2020-07-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.184 Å)
主引用文献Crystal structure of human caspase-4
To Be Published
6NS7
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BU of 6ns7 by Molmil
Crystal structure of murine caspase-11
分子名称: Caspase-11, SULFATE ION
著者Yang, J, Liu, Z, Xiao, T.S.
登録日2019-01-24
公開日2020-07-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of murine caspase-11
To Be Published
6PZP
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BU of 6pzp by Molmil
Crystal structure of caspase-1 in complex with VX-765
分子名称: Caspase-1, N-(4-amino-3-chlorobenzene-1-carbonyl)-3-methyl-L-valyl-N-[(2S)-1-carboxy-3-oxopropan-2-yl]-L-prolinamide
著者Yang, J, Liu, Z, Xiao, T.S.
登録日2019-08-01
公開日2020-08-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal structure of caspase-1 in complex with VX-765
To Be Published
5WQ6
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BU of 5wq6 by Molmil
Crystal Structure of hMNDA-PYD with MBP tag
分子名称: 1,2-ETHANEDIOL, ACETATE ION, MBP tagged hMNDA-PYD, ...
著者Jin, T.C, Xiao, T.S.
登録日2016-11-23
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.648 Å)
主引用文献Design of an expression system to enhance MBP-mediated crystallization
Sci Rep, 7, 2017
5WPZ
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BU of 5wpz by Molmil
Crystal structure of MNDA PYD with MBP tag
分子名称: MBP-hMNDA-PYD, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Jin, T.C, Xiao, T.S.
登録日2016-11-22
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Design of an expression system to enhance MBP-mediated crystallization
Sci Rep, 7, 2017
5H7N
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BU of 5h7n by Molmil
Crystal structure of human NLRP12-PYD with a MBP tag
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NLRP12-PYD with MBP tag, ...
著者Jin, T.C, Xiao, T.S.
登録日2016-11-19
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献Design of an expression system to enhance MBP-mediated crystallization
Sci Rep, 7, 2017
5H7Q
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BU of 5h7q by Molmil
Crystal structure of human MNDA PYD domain with MBP tag
分子名称: ACETATE ION, MNDA PYD domain with MBP tag, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Jin, T.C, Xiao, T.S.
登録日2016-11-20
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Design of an expression system to enhance MBP-mediated crystallization
Sci Rep, 7, 2017
4LQC
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BU of 4lqc by Molmil
The crystal structures of the Brucella protein TcpB and the TLR adaptor protein TIRAP show structural differences in microbial TIR mimicry.
分子名称: TcpB
著者Snyder, G.A, Smith, P, Fresquez, T, Cirl, C, Jiang, J, Snyder, N, Luchetti, T, Miethke, T, Xiao, T.S.
登録日2013-07-17
公開日2013-12-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of the Toll/Interleukin-1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry.
J.Biol.Chem., 289, 2014
4LQD
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BU of 4lqd by Molmil
The crystal structures of the Brucella protein TcpB and the TLR adaptor protein TIRAP show structural differences in microbial TIR mimicry
分子名称: GLYCEROL, Toll/interleukin-1 receptor domain-containing adapter protein
著者Snyder, G.A, Smith, P, Jiang, J, Xiao, T.S.
登録日2013-07-17
公開日2013-12-04
最終更新日2014-04-09
実験手法X-RAY DIFFRACTION (2.451 Å)
主引用文献Crystal structures of the Toll/Interleukin-1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry.
J.Biol.Chem., 289, 2014
4M6B
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BU of 4m6b by Molmil
Crystal structure of yeast Swr1-Z domain in complex with H2A.Z-H2B dimer
分子名称: Chimera protein of Histone H2B.1 and Histone H2A.Z, Helicase SWR1
著者Hong, J.J, Feng, H.Q, Wang, F, Ranjan, A, Chen, J.H, Jiang, J.S, Girlando, R, Xiao, T.S, Wu, C, Bai, Y.W.
登録日2013-08-09
公開日2014-02-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献The Catalytic Subunit of the SWR1 Remodeler Is a Histone Chaperone for the H2A.Z-H2B Dimer.
Mol.Cell, 53, 2014
3VD8
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BU of 3vd8 by Molmil
Crystal structure of human AIM2 PYD domain with MBP fusion
分子名称: 1,2-ETHANEDIOL, Maltose-binding periplasmic protein, Interferon-inducible protein AIM2, ...
著者Jin, T.C, Perry, A, Smith, P, Xiao, T.S.
登録日2012-01-04
公開日2013-01-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.0685 Å)
主引用文献Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly.
J.Biol.Chem., 288, 2013
4EO7
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BU of 4eo7 by Molmil
Crystal structure of the TIR domain of human myeloid differentiation primary response protein 88.
分子名称: MAGNESIUM ION, Myeloid differentiation primary response protein MyD88
著者Snyder, G.A, Cirl, C, Jiang, J.S, Chen, P, Smith, T, Xiao, T.S.
登録日2012-04-13
公開日2013-04-10
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.449 Å)
主引用文献Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli.
Proc.Natl.Acad.Sci.USA, 110, 2013
6N9N
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BU of 6n9n by Molmil
Crystal structure of murine GSDMD
分子名称: Gasdermin-D
著者Liu, Z, Wang, C, Yang, J, Xiao, T.S.
登録日2018-12-03
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.
Immunity, 51, 2019
6N9O
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BU of 6n9o by Molmil
Crystal structure of human GSDMD
分子名称: Gasdermin-D
著者Liu, Z, Wang, C, Yang, J, Xiao, T.S.
登録日2018-12-03
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.
Immunity, 51, 2019
5Y3S
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BU of 5y3s by Molmil
Crystal structure of human NLRP1 leucine rich repeat domain
分子名称: NACHT, LRR and PYD domains-containing protein 1, PHOSPHATE ION, ...
著者Jin, T, Xiao, T.S.
登録日2017-07-30
公開日2018-08-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.451 Å)
主引用文献Crystal structure of human NLRP1 LRR domain
To Be Published
5Z7D
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BU of 5z7d by Molmil
p204HINab-dsDNA complex structure
分子名称: DNA (5'-D(P*CP*CP*AP*TP*CP*AP*GP*AP*AP*AP*GP*AP*GP*AP*GP*C)-3'), Interferon-activable protein 204
著者Jin, T, Jiang, J, Xiao, T.S.
登録日2018-01-28
公開日2019-01-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structural mechanism of DNA recognition by the p204 HIN domain.
Nucleic Acids Res., 2021
6AO4
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BU of 6ao4 by Molmil
Crystal structure of the human gasdermin D C-terminal domain
分子名称: Gasdermin-D
著者Liu, Z, Wang, C, Yang, J, Xiao, T.S.
登録日2017-08-15
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition.
Structure, 26, 2018

 

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