6BZ9
| Crystal structure of human caspase-1 in complex with Ac-FLTD-CMK | 分子名称: | Ac-FLTD-CMK, Caspase-1, DI(HYDROXYETHYL)ETHER | 著者 | Xiao, T.S, Yang, J, Liu, Z, Wang, C, Yang, R. | 登録日 | 2017-12-22 | 公開日 | 2018-06-13 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.796 Å) | 主引用文献 | Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8T5Q
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8T5P
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4QLC
| Crystal structure of chromatosome at 3.5 angstrom resolution | 分子名称: | CITRIC ACID, DNA (167-mer), H5, ... | 著者 | Jiang, J.S, Zhou, B.R, Xiao, T.S, Bai, Y.W. | 登録日 | 2014-06-11 | 公開日 | 2015-07-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.503 Å) | 主引用文献 | Structural Mechanisms of Nucleosome Recognition by Linker Histones. Mol.Cell, 33 Suppl 1, 2015
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6UP4
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6UP3
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6UP2
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6VIE
| Structure of caspase-1 in complex with gasdermin D | 分子名称: | Caspase-1 subunit p10, Caspase-1 subunit p20, Gasdermin-D | 著者 | Liu, Z, Xiao, T.S. | 登録日 | 2020-01-13 | 公開日 | 2020-07-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage. Immunity, 53, 2020
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6NRY
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6NS7
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6PZP
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5WQ6
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5WPZ
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5H7N
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5H7Q
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4LQC
| The crystal structures of the Brucella protein TcpB and the TLR adaptor protein TIRAP show structural differences in microbial TIR mimicry. | 分子名称: | TcpB | 著者 | Snyder, G.A, Smith, P, Fresquez, T, Cirl, C, Jiang, J, Snyder, N, Luchetti, T, Miethke, T, Xiao, T.S. | 登録日 | 2013-07-17 | 公開日 | 2013-12-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of the Toll/Interleukin-1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry. J.Biol.Chem., 289, 2014
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4LQD
| The crystal structures of the Brucella protein TcpB and the TLR adaptor protein TIRAP show structural differences in microbial TIR mimicry | 分子名称: | GLYCEROL, Toll/interleukin-1 receptor domain-containing adapter protein | 著者 | Snyder, G.A, Smith, P, Jiang, J, Xiao, T.S. | 登録日 | 2013-07-17 | 公開日 | 2013-12-04 | 最終更新日 | 2014-04-09 | 実験手法 | X-RAY DIFFRACTION (2.451 Å) | 主引用文献 | Crystal structures of the Toll/Interleukin-1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry. J.Biol.Chem., 289, 2014
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4M6B
| Crystal structure of yeast Swr1-Z domain in complex with H2A.Z-H2B dimer | 分子名称: | Chimera protein of Histone H2B.1 and Histone H2A.Z, Helicase SWR1 | 著者 | Hong, J.J, Feng, H.Q, Wang, F, Ranjan, A, Chen, J.H, Jiang, J.S, Girlando, R, Xiao, T.S, Wu, C, Bai, Y.W. | 登録日 | 2013-08-09 | 公開日 | 2014-02-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | The Catalytic Subunit of the SWR1 Remodeler Is a Histone Chaperone for the H2A.Z-H2B Dimer. Mol.Cell, 53, 2014
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3VD8
| Crystal structure of human AIM2 PYD domain with MBP fusion | 分子名称: | 1,2-ETHANEDIOL, Maltose-binding periplasmic protein, Interferon-inducible protein AIM2, ... | 著者 | Jin, T.C, Perry, A, Smith, P, Xiao, T.S. | 登録日 | 2012-01-04 | 公開日 | 2013-01-16 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.0685 Å) | 主引用文献 | Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly. J.Biol.Chem., 288, 2013
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4EO7
| Crystal structure of the TIR domain of human myeloid differentiation primary response protein 88. | 分子名称: | MAGNESIUM ION, Myeloid differentiation primary response protein MyD88 | 著者 | Snyder, G.A, Cirl, C, Jiang, J.S, Chen, P, Smith, T, Xiao, T.S. | 登録日 | 2012-04-13 | 公開日 | 2013-04-10 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.449 Å) | 主引用文献 | Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli. Proc.Natl.Acad.Sci.USA, 110, 2013
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6N9N
| Crystal structure of murine GSDMD | 分子名称: | Gasdermin-D | 著者 | Liu, Z, Wang, C, Yang, J, Xiao, T.S. | 登録日 | 2018-12-03 | 公開日 | 2019-06-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization. Immunity, 51, 2019
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6N9O
| Crystal structure of human GSDMD | 分子名称: | Gasdermin-D | 著者 | Liu, Z, Wang, C, Yang, J, Xiao, T.S. | 登録日 | 2018-12-03 | 公開日 | 2019-06-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization. Immunity, 51, 2019
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5Y3S
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5Z7D
| p204HINab-dsDNA complex structure | 分子名称: | DNA (5'-D(P*CP*CP*AP*TP*CP*AP*GP*AP*AP*AP*GP*AP*GP*AP*GP*C)-3'), Interferon-activable protein 204 | 著者 | Jin, T, Jiang, J, Xiao, T.S. | 登録日 | 2018-01-28 | 公開日 | 2019-01-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | 主引用文献 | Structural mechanism of DNA recognition by the p204 HIN domain. Nucleic Acids Res., 2021
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6AO4
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