1ZSQ
| Crystal Structure of MTMR2 in complex with phosphatidylinositol 3-phosphate | 分子名称: | 1,2-ETHANEDIOL, 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, Myotubularin-related protein 2 | 著者 | Begley, M.J, Taylor, G.S, Brock, M.A, Ghosh, P, Woods, V.L, Dixon, J.E. | 登録日 | 2005-05-25 | 公開日 | 2006-01-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
1ZVR
| Crystal Structure of MTMR2 in complex with phosphatidylinositol 3,5-bisphosphate | 分子名称: | (1S)-2-(1-HYDROXYBUTOXY)-1-{[(HYDROXY{[(2R,3S,5R,6S)-2,4,6-TRIHYDROXY-3,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTYRATE, 1,2-ETHANEDIOL, Myotubularin-related protein 2 | 著者 | Begley, M.J, Taylor, G.S, Brock, M.A, Ghosh, P, Woods, V.L, Dixon, J.E. | 登録日 | 2005-06-02 | 公開日 | 2006-01-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
3T5N
| 1.8A crystal structure of Lassa virus nucleoprotein in complex with ssRNA | 分子名称: | NICKEL (II) ION, Nucleoprotein, RNA (5'-R(P*UP*AP*UP*CP*UP*C)-3') | 著者 | Hastie, K.M, Liu, T, King, L.B, Ngo, N, Zandonatti, M.A, Woods, V.L, de la Torre, J.C, Saphire, E.O. | 登録日 | 2011-07-27 | 公開日 | 2012-01-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.787 Å) | 主引用文献 | Crystal structure of the Lassa virus nucleoprotein-RNA complex reveals a gating mechanism for RNA binding. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
3T5Q
| 3A structure of Lassa virus nucleoprotein in complex with ssRNA | 分子名称: | Nucleoprotein, PHOSPHATE ION, RNA (5'-R(P*UP*AP*UP*CP*UP*C)-3'), ... | 著者 | Hastie, K.M, Liu, T, King, L.B, Ngo, N, Zandonatti, M.A, Woods, V.L, de la Torre, J.C, Saphire, E.O. | 登録日 | 2011-07-27 | 公開日 | 2012-01-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of the Lassa virus nucleoprotein-RNA complex reveals a gating mechanism for RNA binding. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
4F7Z
| Conformational dynamics of exchange protein directly activated by cAMP | 分子名称: | GLYCEROL, Rap guanine nucleotide exchange factor 4 | 著者 | White, M.A, Tsalkova, T.N, Mei, F.C, Liu, T, Woods, V.L, Cheng, X. | 登録日 | 2012-05-16 | 公開日 | 2012-10-03 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural analyses of a constitutively active mutant of exchange protein directly activated by cAMP. Plos One, 7, 2012
|
|
3KS4
| Crystal structure of Reston ebolavirus VP35 RNA binding domain | 分子名称: | Polymerase cofactor VP35 | 著者 | Kimberlin, C.R, Bornholdt, Z.A, Li, S, Woods, V.L, Macrae, I.J, Saphire, E.O. | 登録日 | 2009-11-20 | 公開日 | 2010-01-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression. Proc.Natl.Acad.Sci.USA, 107, 2009
|
|
3KS8
| Crystal structure of Reston ebolavirus VP35 RNA binding domain in complex with 18bp dsRNA | 分子名称: | 5'-R(*AP*GP*AP*AP*GP*GP*AP*GP*GP*GP*AP*GP*GP*GP*AP*GP*GP*A)-3', 5'-R(*UP*CP*CP*UP*CP*CP*CP*UP*CP*CP*CP*UP*CP*CP*UP*UP*CP*U)-3', Polymerase cofactor VP35 | 著者 | Kimberlin, C.R, Bornholdt, Z.A, Li, S, Woods, V.L, Macrae, I.J, Saphire, E.O. | 登録日 | 2009-11-20 | 公開日 | 2010-01-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression. Proc.Natl.Acad.Sci.USA, 107, 2009
|
|
5I72
| Crystal structure of the oligomeric form of the Lassa virus matrix protein Z | 分子名称: | RING finger protein Z, ZINC ION | 著者 | Hastie, K, Zandonatti, M, Liu, T, Li, S, Woods Jr, V, Saphire, E.O. | 登録日 | 2016-02-16 | 公開日 | 2016-03-09 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal Structure of the Oligomeric Form of Lassa Virus Matrix Protein Z. J.Virol., 90, 2016
|
|
3VE0
| Crystal structure of Sudan Ebolavirus Glycoprotein (strain Boniface) bound to 16F6 | 分子名称: | 16F6 Antibody chain A, 16F6 Antibody chain B, Envelope glycoprotein, ... | 著者 | Saphire, E.O, Bale, S, Dias, J.M. | 登録日 | 2012-01-06 | 公開日 | 2012-04-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.353 Å) | 主引用文献 | Structural basis for differential neutralization of ebolaviruses. Viruses, 4, 2012
|
|
4CSF
| |
3COC
| |
3COD
| Crystal Structure of T90A/D115A mutant of Bacteriorhodopsin | 分子名称: | Bacteriorhodopsin, RETINAL | 著者 | Joh, N.H, Min, A, Faham, S, Bowie, J.U. | 登録日 | 2008-03-27 | 公開日 | 2008-04-08 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins. Nature, 453, 2008
|
|
3R1B
| Open crystal structure of cytochrome P450 2B4 covalently bound to the mechanism-based inactivator tert-butylphenylacetylene | 分子名称: | (4-tert-butylphenyl)acetaldehyde, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, ... | 著者 | Gay, S.C, Zhang, H, Stout, C.D, Hollenberg, P.F, Halpert, J.R. | 登録日 | 2011-03-09 | 公開日 | 2011-05-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Analysis of Mammalian Cytochrome P450 2B4 Covalently Bound to the Mechanism-Based Inactivator tert-Butylphenylacetylene: Insight into Partial Enzymatic Activity. Biochemistry, 50, 2011
|
|
3R1A
| Closed crystal structure of cytochrome P450 2B4 covalently bound to the mechanism-based inactivator tert-butylphenylacetylene | 分子名称: | (4-tert-butylphenyl)acetaldehyde, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Gay, S.C, Zhang, H, Stout, C.D, Hollenberg, P.F, Halpert, J.R. | 登録日 | 2011-03-09 | 公開日 | 2011-05-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural Analysis of Mammalian Cytochrome P450 2B4 Covalently Bound to the Mechanism-Based Inactivator tert-Butylphenylacetylene: Insight into Partial Enzymatic Activity. Biochemistry, 50, 2011
|
|
3UAS
| Cytochrome P450 2B4 covalently bound to the mechanism-based inactivator 9-ethynylphenanthrene | 分子名称: | 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Gay, S.C, Zhang, H, Shah, M.B, Stout, C.D, Halpert, J.R, Hollenberg, P.F. | 登録日 | 2011-10-21 | 公開日 | 2013-01-09 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.939 Å) | 主引用文献 | Potent Mechanism-Based Inactivation of Cytochrome P450 2B4 by 9-Ethynylphenanthrene: Implications for Allosteric Modulation of Cytochrome P450 Catalysis. Biochemistry, 52, 2013
|
|
3TK3
| Cytochrome P450 2B4 mutant L437A in complex with 4-(4-chlorophenyl)imidazole | 分子名称: | 4-(4-CHLOROPHENYL)IMIDAZOLE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Gay, S.C, Jang, H.H, Wilderman, P.R, Zhang, Q, Stout, C.D, Halpert, J.R. | 登録日 | 2011-08-25 | 公開日 | 2011-11-16 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.8001 Å) | 主引用文献 | Investigation by site-directed mutagenesis of the role of cytochrome P450 2B4 non-active-site residues in protein-ligand interactions based on crystal structures of the ligand-bound enzyme. Febs J., 279, 2012
|
|
4RKK
| Structure of a product bound phosphatase | 分子名称: | Laforin, PHOSPHATE ION, alpha-D-glucopyranose, ... | 著者 | Vander Kooi, C.W. | 登録日 | 2014-10-13 | 公開日 | 2015-01-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural mechanism of laforin function in glycogen dephosphorylation and lafora disease. Mol.Cell, 57, 2015
|
|
4K3V
| Structure of Staphylococcus aureus MntC | 分子名称: | ABC superfamily ATP binding cassette transporter, binding protein, MANGANESE (II) ION | 著者 | Parris, K.D, Mosyak, L. | 登録日 | 2013-04-11 | 公開日 | 2013-07-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Three-Dimensional Structure and Biophysical Characterization of Staphylococcus aureus Cell Surface Antigen-Manganese Transporter MntC. J.Mol.Biol., 425, 2013
|
|
1VJL
| |
1O5L
| |
3QAM
| Crystal Structure of Glu208Ala mutant of catalytic subunit of cAMP-dependent protein kinase | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein kinase inhibitor, ... | 著者 | Yang, J, Wu, J, Steichen, J, Taylor, S.S. | 登録日 | 2011-01-11 | 公開日 | 2011-12-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold. J.Mol.Biol., 415, 2012
|
|
3QAL
| Crystal Structure of Arg280Ala mutant of Catalytic subunit of cAMP-dependent Protein Kinase | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein kinase inhibitor, ... | 著者 | Yang, J, Wu, J, Steichen, J, Taylor, S.S. | 登録日 | 2011-01-11 | 公開日 | 2011-12-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold. J.Mol.Biol., 415, 2012
|
|
3SHR
| Crystal Structure of cGMP-dependent Protein Kinase Reveals Novel Site of Interchain Communication | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cGMP-dependent protein kinase 1 | 著者 | Osborne, B.W, Wu, J, Taylor, S.S, Dostmann, W.R. | 登録日 | 2011-06-16 | 公開日 | 2011-09-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication. Structure, 19, 2011
|
|
3H16
| Crystal structure of a bacteria TIR domain, PdTIR from Paracoccus denitrificans | 分子名称: | SULFATE ION, TIR protein | 著者 | Chan, S.L, Low, L.Y, Santelli, E, Pascual, J. | 登録日 | 2009-04-11 | 公開日 | 2009-06-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular Mimicry in Innate Immunity: CRYSTAL STRUCTURE OF A BACTERIAL TIR DOMAIN. J.Biol.Chem., 284, 2009
|
|
4CSG
| |