4F7Z

Conformational dynamics of exchange protein directly activated by cAMP

Summary for 4F7Z

Entry DOI	10.2210/pdb4f7z/pdb
Descriptor	Rap guanine nucleotide exchange factor 4, GLYCEROL (3 entities in total)
Functional Keywords	cyclic nucleotide, gef, exchange factor, regulation, auto-inhibition, cdc25 homology domain, exocytosis
Biological source	Mus musculus (mouse)
Cellular location	Cytoplasm: Q9EQZ6
Total number of polymer chains	1
Total formula weight	114705.10
Authors	White, M.A.,Tsalkova, T.N.,Mei, F.C.,Liu, T.,Woods, V.L.,Cheng, X. (deposition date: 2012-05-16, release date: 2012-10-03, Last modification date: 2023-09-13)
Primary citation	White, M.A.,Li, S.,Tsalkova, T.,Mei, F.C.,Liu, T.,Woods, V.L.,Cheng, X. Structural analyses of a constitutively active mutant of exchange protein directly activated by cAMP. Plos One, 7:e49932-e49932, 2012 Cited by PubMed: 23189173 DOI: 10.1371/journal.pone.0049932 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation