4F7Z
Conformational dynamics of exchange protein directly activated by cAMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Rap guanine nucleotide exchange factor 4 | polymer | 999 | 114060.4 | 1 | UniProt (Q9EQZ6) Pfam (PF00027) Pfam (PF00610) Pfam (PF00618) Pfam (PF00617) | Mus musculus (mouse) | Epac2, Exchange factor directly activated by cAMP 2, Exchange protein directly activated by cAMP 2, EPAC 2, cAMP-dependent Rap1 guanine-nucleotide exchange factor, cAMP-regulated guanine nucleotide exchange factor II, cAMP-GEFII |
| 2 | B, C, D, E, F... (A) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 3 | I (A) | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence modifications
A: 1 - 993 (UniProt: Q9EQZ6)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Ser -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ile -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Gly 435 | Phe 435 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 114060.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 644.7 | |
| All* | Total formula weight | 114705.1 |
