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Human p38 MAP Kinase in Complex with an Imidazo-pyridine
Descriptor:	2-({4-[(4-benzylpiperidin-1-yl)carbonyl]benzyl}sulfanyl)-3H-imidazo[4,5-c]pyridine, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
Authors:	Gruetter, C, Simard, J.R, Rauh, D.
Deposit date:	2009-09-02
Release date:	2009-11-17
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	High-Throughput Screening To Identify Inhibitors Which Stabilize Inactive Kinase Conformations in p38alpha J.Am.Chem.Soc., 131, 2009

3ED8

Application of the superfolder YFP bimolecular fluorescence complementation for studying protein-protein interactions in vitro
Descriptor:	yellow fluorescence protein
Authors:	Ottmann, C, Weyand, M.
Deposit date:	2008-09-02
Release date:	2009-01-20
Last modified:	2022-12-21
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Applicability of superfolder YFP bimolecular fluorescence complementation in vitro. Biol.Chem., 390, 2009

7OBH

Crystal structure of 14-3-3 sigma in complex with NPM1 phosphopeptide and stabilizer Fusicoccin-A
Descriptor:	14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ...
Authors:	Centorrino, F, Andlovic, B, Ottmann, C.
Deposit date:	2021-04-22
Release date:	2022-05-04
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023

7OBX

Crystal structure of 14-3-3 sigma in complex with SSBP4 phosphopeptide
Descriptor:	14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ...
Authors:	Centorrino, F, Andlovic, B, Ottmann, C.
Deposit date:	2021-04-23
Release date:	2022-05-04
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023

7OBY

Crystal structure of 14-3-3 sigma in complex with SSBP4 phosphopeptide and stabilizer Fusicoccin-A
Descriptor:	14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ...
Authors:	Centorrino, F, Andlovic, B, Ottmann, C.
Deposit date:	2021-04-24
Release date:	2022-05-04
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023

7OBG

Crystal structure of 14-3-3 sigma in complex with NPM1 phosphopeptide
Descriptor:	14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ...
Authors:	Centorrino, F, Andlovic, B, Ottmann, C.
Deposit date:	2021-04-22
Release date:	2022-05-04
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023

7OBS

Crystal structure of 14-3-3 sigma in complex with RIPK2 phosphopeptide
Descriptor:	14-3-3 protein sigma, CALCIUM ION, MAGNESIUM ION, ...
Authors:	Centorrino, F, Andlovic, B, Ottmann, C.
Deposit date:	2021-04-23
Release date:	2022-05-04
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023

7OBD

Crystal structure of 14-3-3 sigma in complex with Phosphorylated and Farnesylated Rnd3 peptide and stabilizer Fusicoccin-A
Descriptor:	14-3-3 protein sigma, CHLORIDE ION, FARNESYL, ...
Authors:	Centorrino, F, Andlovic, B, Ottmann, C.
Deposit date:	2021-04-21
Release date:	2022-05-04
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023

7OB8

Crystal structure of 14-3-3 sigma in complex with LDB1 phosphopeptide and stabilizer Fusicoccin-A
Descriptor:	14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ...
Authors:	Centorrino, F, Andlovic, B, Ottmann, C.
Deposit date:	2021-04-21
Release date:	2022-05-04
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023

7OBT

Crystal structure of 14-3-3 sigma in complex with RIPK2 phosphopeptide and stabilizer Fusicoccin-A
Descriptor:	14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ...
Authors:	Centorrino, F, Andlovic, B, Ottmann, C.
Deposit date:	2021-04-23
Release date:	2022-05-04
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023

7OBK

Crystal structure of 14-3-3 sigma in complex with PKR phosphopeptide
Descriptor:	14-3-3 protein sigma, MAGNESIUM ION, PKR phosphopeptide
Authors:	Centorrino, F, Andlovic, B, Ottmann, C.
Deposit date:	2021-04-22
Release date:	2022-05-04
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023

7OB5

Crystal structure of 14-3-3 sigma in complex with LDB1 phosphopeptide
Descriptor:	14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ...
Authors:	Centorrino, F, Andlovic, B, Ottmann, C.
Deposit date:	2021-04-21
Release date:	2022-05-04
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023

7OBL

Crystal structure of 14-3-3 sigma in complex with PKR phosphopeptide and stabilizer Fusicoccin-A
Descriptor:	14-3-3 protein sigma, FUSICOCCIN, MAGNESIUM ION, ...
Authors:	Centorrino, F, Andlovic, B, Ottmann, C.
Deposit date:	2021-04-22
Release date:	2022-05-04
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023

7OBC

Crystal structure of 14-3-3 sigma in complex with Phosphorylated and Farnesylated Rnd3 peptide
Descriptor:	14-3-3 protein sigma, CHLORIDE ION, FARNESYL, ...
Authors:	Centorrino, F, Andlovic, B, Ottmann, C.
Deposit date:	2021-04-21
Release date:	2022-05-04
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023

4EHM

RabGGTase in complex with covalently bound Psoromic acid
Descriptor:	4-formyl-3-hydroxy-8-methoxy-1,9-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-6-carboxylic acid, CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, ...
Authors:	Guo, Z, Deraeve, C, Bon, R.S, Alexandrov, K, Waldmann, H, Wu, Y.W, Goody, R.S, Blankenfeldt, W.
Deposit date:	2012-04-02
Release date:	2012-05-30
Last modified:	2017-08-09
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Psoromic Acid is a Selective and Covalent Rab-Prenylation Inhibitor Targeting Autoinhibited RabGGTase J.Am.Chem.Soc., 134, 2012

4CCO

60S ribosomal protein L8 histidine hydroxylase (NO66 S373C) in complex with Mn(II), N-oxalylglycine (NOG) and 60S ribosomal protein L8 (RPL8 G214C) peptide fragment (complex-3)
Descriptor:	1,2-ETHANEDIOL, 60S RIBOSOMAL PROTEIN L8, BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE NO66, ...
Authors:	Chowdhury, R, Schofield, C.J.
Deposit date:	2013-10-23
Release date:	2014-05-14
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Nature, 510, 2014

4CCM

60S ribosomal protein L8 histidine hydroxylase (NO66) in complex with Mn(II), N-oxalylglycine (NOG) and 60S ribosomal protein L8 (RPL8 G220C) peptide fragment (complex-1)
Descriptor:	1,2-ETHANEDIOL, 60S RIBOSOMAL PROTEIN L8, BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE NO66, ...
Authors:	Chowdhury, R, Schofield, C.J.
Deposit date:	2013-10-23
Release date:	2014-05-14
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (2.51 Å)
Cite:	Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Nature, 510, 2014

4BXF

60S ribosomal protein L27A histidine hydroxylase (MINA53 Y209C) in complex with MN(II), 2-oxoglutarate (2OG) and 60S ribosomal protein L27A (RPL27A G37C) peptide fragment
Descriptor:	2-OXOGLUTARIC ACID, 60S RIBOSOMAL PROTEIN L27A, BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE MINA, ...
Authors:	Chowdhury, R, Schofield, C.J.
Deposit date:	2013-07-10
Release date:	2014-05-14
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (2.05 Å)
Cite:	Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Nature, 510, 2014

4CCN

60S ribosomal protein L8 histidine hydroxylase (NO66 L299C/C300S) in complex with Mn(II), N-oxalylglycine (NOG) and 60S ribosomal protein L8 (RPL8 G220C) peptide fragment (complex-2)
Descriptor:	1,2-ETHANEDIOL, 60S RIBOSOMAL PROTEIN L8, BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE NO66, ...
Authors:	Chowdhury, R, Schofield, C.J.
Deposit date:	2013-10-23
Release date:	2014-05-14
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (2.23 Å)
Cite:	Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Nature, 510, 2014

4BU2

60S ribosomal protein L27A histidine hydroxylase (MINA53) in complex with Ni(II) and 2-oxoglutarate (2OG)
Descriptor:	1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE MINA, ...
Authors:	Chowdhury, R, Clifton, I.J, McDonough, M.A, Ng, S.S, Pilka, E, Oppermann, U, Schofield, C.J.
Deposit date:	2013-06-19
Release date:	2014-05-14
Last modified:	2019-02-06
Method:	X-RAY DIFFRACTION (2.78 Å)
Cite:	Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Nature, 510, 2014

4CCK

60S ribosomal protein L8 histidine hydroxylase (NO66) in complex with Mn(II) and N-oxalylglycine (NOG)
Descriptor:	1,2-ETHANEDIOL, BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE NO66, MANGANESE (II) ION, ...
Authors:	Chowdhury, R, Ge, W, Clifton, I.J, Schofield, C.J.
Deposit date:	2013-10-23
Release date:	2014-05-14
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (2.15 Å)
Cite:	Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Nature, 510, 2014

4CCJ

60S ribosomal protein L8 histidine hydroxylase (NO66) in apo form
Descriptor:	1,2-ETHANEDIOL, BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE NO66
Authors:	Chowdhury, R, Ge, W, Clifton, I.J, Schofield, C.J.
Deposit date:	2013-10-23
Release date:	2014-05-14
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (2.15 Å)
Cite:	Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Nature, 510, 2014

6EW9

CRYSTAL STRUCTURE OF DEGS STRESS SENSOR PROTEASE IN COMPLEX WITH ACTIVATING DNRLGLVYQF PEPTIDE
Descriptor:	CALCIUM ION, DI(HYDROXYETHYL)ETHER, DNRLGLVYQF PEPTIDE, ...
Authors:	Vetter, I.R, Porfetye, A.T, Stege, P.
Deposit date:	2017-11-03
Release date:	2018-04-25
Last modified:	2018-11-07
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Identification of Noncatalytic Lysine Residues from Allosteric Circuits via Covalent Probes. ACS Chem. Biol., 13, 2018

4GTO

FTase in complex with BMS analogue 14
Descriptor:	4-({(3R)-7-cyano-4-[(4-methoxyphenyl)sulfonyl]-1-[(1-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-3-yl}methyl)phenyl trifluoromethanesulfonate, DIMETHYL SULFOXIDE, FARNESYL DIPHOSPHATE, ...
Authors:	Guo, Z, Stigter, E.A, Bon, R.S, Waldmann, H, Blankenfeldt, W, Goody, R.S.
Deposit date:	2012-08-29
Release date:	2012-10-24
Last modified:	2023-11-08
Method:	X-RAY DIFFRACTION (2.15 Å)
Cite:	Development of Selective, Potent RabGGTase Inhibitors J.Med.Chem., 55, 2012

4GTM

FTase in complex with BMS analogue 11
Descriptor:	4-({(3R)-7-cyano-4-[(4-methoxyphenyl)sulfonyl]-1-[(1-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-3-yl}methyl)phenyl hexylcarbamate, DIMETHYL SULFOXIDE, FARNESYL DIPHOSPHATE, ...
Authors:	Guo, Z, Stigter, E.A, Bon, R.S, Waldmann, H, Blankenfeldt, W, Goody, R.S.
Deposit date:	2012-08-28
Release date:	2012-10-24
Last modified:	2023-11-08
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Development of Selective, Potent RabGGTase Inhibitors J.Med.Chem., 55, 2012

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Total results:	74
Displayed results:	25
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