4BXF

60S ribosomal protein L27A histidine hydroxylase (MINA53 Y209C) in complex with MN(II), 2-oxoglutarate (2OG) and 60S ribosomal protein L27A (RPL27A G37C) peptide fragment

Summary for 4BXF

Related2XDV 4BU2 4CCJ 4CCK 4CCM 4CCN 4CCO 4DIQ
DescriptorBIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE MINA, 60S RIBOSOMAL PROTEIN L27A, MANGANESE (II) ION, ... (5 entities in total)
Functional Keywordsoxidoreductase-translation complex, oxidoreductase, non-heme, iron-binding, dsbh, dioxygenase, jmjc domain, ribosome biogenesis, nuclear protein, beta-hydroxylation, transcription and epigenetic regulation, signaling, oxidoreductase/translation
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains4
Total molecular weight105705.63
Authors
Chowdhury, R.,Schofield, C.J. (deposition date: 2013-07-10, release date: 2014-05-14, Last modification date: 2019-01-30)
Primary citation
Chowdhury, R.,Sekirnik, R.,Brissett, N.C.,Krojer, T.,Ho, C.H.,Ng, S.S.,Clifton, I.J.,Ge, W.,Kershaw, N.J.,Fox, G.C.,Muniz, J.R.C.,Vollmar, M.,Phillips, C.,Pilka, E.S.,Kavanagh, K.L.,von Delft, F.,Oppermann, U.,McDonough, M.A.,Doherty, A.J.,Schofield, C.J.
Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 510:422-426, 2014
PubMed: 24814345 (PDB entries with the same primary citation)
DOI: 10.1038/nature13263
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.05 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers70 1.6% 5.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4bxf
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Molmil generated image of 4bxf
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Molmil generated image of 4bxf
rotated about y axis by 90°
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