4CCK

60S ribosomal protein L8 histidine hydroxylase (NO66) in complex with Mn(II) and N-oxalylglycine (NOG)

Summary for 4CCK

Related2XDV 4BU2 4BXF 4CCJ 4CCM 4CCN 4CCO 4DIQ
DescriptorBIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE NO66, MANGANESE (II) ION, N-OXALYLGLYCINE, ... (5 entities in total)
Functional Keywordsoxidoreductase, non-heme, iron-binding, dsbh, 2-oxoglutarate, dioxygenase, jmjc domain, ribosome biogenesis, nuclear protein, rpl8, beta-hydroxylation, transcription and epigenetic regulation, signaling
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains4
Total molecular weight214021.13
Authors
Chowdhury, R.,Ge, W.,Clifton, I.J.,Schofield, C.J. (deposition date: 2013-10-23, release date: 2014-05-14, Last modification date: 2019-02-06)
Primary citation
Chowdhury, R.,Sekirnik, R.,Brissett, N.C.,Krojer, T.,Ho, C.H.,Ng, S.S.,Clifton, I.J.,Ge, W.,Kershaw, N.J.,Fox, G.C.,Muniz, J.R.C.,Vollmar, M.,Phillips, C.,Pilka, E.S.,Kavanagh, K.L.,von Delft, F.,Oppermann, U.,McDonough, M.A.,Doherty, A.J.,Schofield, C.J.
Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 510:422-426, 2014
PubMed: 24814345 (PDB entries with the same primary citation)
DOI: 10.1038/nature13263
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.15 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.207100 2.2% 1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4cck
no rotation
Molmil generated image of 4cck
rotated about x axis by 90°
Molmil generated image of 4cck
rotated about y axis by 90°
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