4CCK
60S ribosomal protein L8 histidine hydroxylase (NO66) in complex with Mn(II) and N-oxalylglycine (NOG)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE NO66 | polymer | 467 | 53241.2 | 4 | UniProt (Q9H6W3) Pfam (PF08007) Pfam (PF21233) | HOMO SAPIENS (HUMAN) | 60S RIBOSOMAL PROTEIN L8 HISTIDINE HYDROXYLASE, HISTONE LYSINE DEMETHYLASE NO66, MYC-ASSOCIATED PROTEIN WITH JMJC DOMAIN, NUCLEOLAR PROTEIN 66, HSNO66, RIBOSOMAL OXYGENASE NO66, ROX |
| 2 | E, H, K, N (A, B, C, D) | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 3 | F, I, L, O (A, B, C, D) | N-OXALYLGLYCINE | non-polymer | 147.1 | 4 | Chemie (OGA) | |||
| 4 | G, J, M, P (A, B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 829 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 183 - 641 (UniProt: Q9H6W3)
| PDB | External Database | Details |
|---|---|---|
| Met 182 | - | expression tag |
| Ala 642 | - | expression tag |
| Glu 643 | - | expression tag |
| Asn 644 | - | expression tag |
| Leu 645 | - | expression tag |
| Tyr 646 | - | expression tag |
| Phe 647 | - | expression tag |
| Gln 648 | - | expression tag |
| Ala 364 | Val 364 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 212964.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1056.4 | |
| All* | Total formula weight | 214021.1 |
