4BU2
60S ribosomal protein L27A histidine hydroxylase (MINA53) in complex with Ni(II) and 2-oxoglutarate (2OG)
Summary for 4BU2
Entry DOI | 10.2210/pdb4bu2/pdb |
Related | 2XDV 4BXF 4CCJ 4CCK 4CCM 4CCN 4CCO 4DIQ |
Descriptor | BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE MINA, NICKEL (II) ION, 2-OXOGLUTARIC ACID, ... (5 entities in total) |
Functional Keywords | oxidoreductase, non-heme, iron-binding, dsbh, 2-oxoglutarate, dioxygenase, jmjc domain, ribosome biogenesis, nuclear protein, rpl27a, beta-hydroxylation, transcription and epigenetic regulation, signaling |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 51349.18 |
Authors | Chowdhury, R.,Clifton, I.J.,McDonough, M.A.,Ng, S.S.,Pilka, E.,Oppermann, U.,Schofield, C.J. (deposition date: 2013-06-19, release date: 2014-05-14, Last modification date: 2019-02-06) |
Primary citation | Chowdhury, R.,Sekirnik, R.,Brissett, N.C.,Krojer, T.,Ho, C.H.,Ng, S.S.,Clifton, I.J.,Ge, W.,Kershaw, N.J.,Fox, G.C.,Muniz, J.R.C.,Vollmar, M.,Phillips, C.,Pilka, E.S.,Kavanagh, K.L.,von Delft, F.,Oppermann, U.,McDonough, M.A.,Doherty, A.J.,Schofield, C.J. Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Nature, 510:422-426, 2014 Cited by PubMed: 24814345DOI: 10.1038/nature13263 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.78 Å) |
Structure validation
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