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1S8F
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BU of 1s8f by Molmil
Crystal structure of Rab9 complexed to GDP reveals a dimer with an active conformation of switch II
Descriptor: BENZOIC ACID, CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Wittmann, J.G, Rudolph, M.G.
Deposit date:2004-02-02
Release date:2004-06-11
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal structure of Rab9 complexed to GDP reveals a dimer with an active conformation of switch II.
Febs Lett., 568, 2004
2QCN
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BU of 2qcn by Molmil
Covalent complex of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase with 6-iodo-UMP
Descriptor: GLYCEROL, SULFATE ION, URIDINE-5'-MONOPHOSPHATE, ...
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCD
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BU of 2qcd by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to UMP
Descriptor: URIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase)
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCF
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BU of 2qcf by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMP
Descriptor: 5-FLUORO-URIDINE-5'-MONOPHOSPHATE, GLYCEROL, Uridine 5'-monophosphate synthase (UMP synthase)
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCE
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BU of 2qce by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to sulfate, glycerol, and chloride
Descriptor: CHLORIDE ION, GLYCEROL, SULFATE ION, ...
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCL
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BU of 2qcl by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to OMP
Descriptor: GLYCEROL, OROTIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase)
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCC
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BU of 2qcc by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase, apo form
Descriptor: GLYCEROL, Orotidine 5'- phosphate decarboxylase (OMPdecase), SULFATE ION
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCM
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BU of 2qcm by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 6-hydroxymethyl-UMP
Descriptor: 6-(HYDROXYMETHYL)URIDINE 5'-(DIHYDROGEN PHOSPHATE), Uridine 5'-monophosphate synthase (UMP synthase)
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCG
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BU of 2qcg by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to 5-bromo-UMP
Descriptor: 5-BROMO-URIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase)
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCH
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BU of 2qch by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to 5-iodo-UMP
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-IODO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, IODIDE ION, ...
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
3LLL
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BU of 3lll by Molmil
Crystal structure of mouse pacsin2 F-BAR domain
Descriptor: CALCIUM ION, CHLORIDE ION, Protein kinase C and casein kinase substrate in neurons protein 2, ...
Authors:Rudolph, M.G.
Deposit date:2010-01-29
Release date:2010-05-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A hinge in the distal end of the PACSIN 2 F-BAR domain may contribute to membrane-curvature sensing.
J.Mol.Biol., 400, 2010
2AFT
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BU of 2aft by Molmil
Formylglycine generating enzyme C336S mutant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Sulfatase modifying factor 1
Authors:Roeser, D, Rudolph, M.G.
Deposit date:2005-07-26
Release date:2005-12-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme
Proc.Natl.Acad.Sci.Usa, 103, 2006
2AFY
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BU of 2afy by Molmil
Formylglycine generating enzyme C341S mutant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Sulfatase modifying factor 1
Authors:Roeser, D, Rudolph, M.G.
Deposit date:2005-07-26
Release date:2005-12-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme
Proc.Natl.Acad.Sci.Usa, 103, 2006
2AIK
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BU of 2aik by Molmil
Formylglycine generating enzyme C336S mutant covalently bound to substrate peptide LCTPSRA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Roeser, D, Rudolph, M.G.
Deposit date:2005-07-29
Release date:2005-12-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme
Proc.Natl.Acad.Sci.Usa, 103, 2006
2AIJ
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BU of 2aij by Molmil
Formylglycine generating enzyme C336S mutant covalently bound to substrate peptide CTPSR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Roeser, D, Rudolph, M.G.
Deposit date:2005-07-29
Release date:2005-12-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme
Proc.Natl.Acad.Sci.Usa, 103, 2006
2AII
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BU of 2aii by Molmil
wild-type Formylglycine generating enzyme reacted with iodoacetamide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETAMIDE, CALCIUM ION, ...
Authors:Roeser, D, Rudolph, M.G.
Deposit date:2005-07-29
Release date:2005-12-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme
Proc.Natl.Acad.Sci.Usa, 103, 2006
2GXS
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BU of 2gxs by Molmil
HERA N-terminal domain in complex with AMP, crystal form 2
Descriptor: ADENOSINE MONOPHOSPHATE, CALCIUM ION, GLYCEROL, ...
Authors:Rudolph, M.G, Klostermeier, D.
Deposit date:2006-05-09
Release date:2006-08-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Crystal Structure and Nucleotide Binding of the Thermus thermophilus RNA Helicase Hera N-terminal Domain.
J.Mol.Biol., 351, 2006
2GXQ
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BU of 2gxq by Molmil
HERA N-terminal domain in complex with AMP, crystal form 1
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE MONOPHOSPHATE, heat resistant RNA dependent ATPase
Authors:Rudolph, M.G, Klostermeier, D.
Deposit date:2006-05-09
Release date:2006-08-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal Structure and Nucleotide Binding of the Thermus thermophilus RNA Helicase Hera N-terminal Domain.
J.Mol.Biol., 351, 2006
2GXU
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BU of 2gxu by Molmil
HERA N-terminal domain in complex with orthophosphate, crystal form 1
Descriptor: PHOSPHATE ION, heat resistant RNA dependent ATPase
Authors:Rudolph, M.G, Klostermeier, D.
Deposit date:2006-05-09
Release date:2006-08-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Crystal Structure and Nucleotide Binding of the Thermus thermophilus RNA Helicase Hera N-terminal Domain.
J.Mol.Biol., 351, 2006

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