2AII

wild-type Formylglycine generating enzyme reacted with iodoacetamide

Summary for 2AII

Entry DOI	10.2210/pdb2aii/pdb
Related	2AIJ 2AIK
Descriptor	Sulfatase modifying factor 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (5 entities in total)
Functional Keywords	formylglycine, post-translational modification, endoplasmic reticulum, sulfatase, hydrolase activator, protein binding
Biological source	Homo sapiens (human)
Cellular location	Endoplasmic reticulum lumen: Q8NBK3
Total number of polymer chains	1
Total formula weight	32690.30
Authors	Roeser, D.,Rudolph, M.G. (deposition date: 2005-07-29, release date: 2005-12-13, Last modification date: 2023-10-25)
Primary citation	Roeser, D.,Preusser-Kunze, A.,Schmidt, B.,Gasow, K.,Wittmann, J.G.,Dierks, T.,von Figura, K.,Rudolph, M.G. A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme Proc.Natl.Acad.Sci.Usa, 103:81-86, 2006 Cited by PubMed: 16368756 DOI: 10.1073/pnas.0507592102 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.54 Å)

Structure validation