2AIJ
Formylglycine generating enzyme C336S mutant covalently bound to substrate peptide CTPSR
Summary for 2AIJ
Entry DOI | 10.2210/pdb2aij/pdb |
Related | 2AII 2AIK |
Descriptor | Sulfatase modifying factor 1, CTPSR peptide from Arylsulfatase A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | formylglycine, post-translational modification, endoplasmic reticulum, sulfatase, hydrolase activator, protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Endoplasmic reticulum lumen: Q8NBK3 Lysosome: P15289 |
Total number of polymer chains | 2 |
Total formula weight | 33214.27 |
Authors | Roeser, D.,Rudolph, M.G. (deposition date: 2005-07-29, release date: 2005-12-13, Last modification date: 2023-10-25) |
Primary citation | Roeser, D.,Preusser-Kunze, A.,Schmidt, B.,Gasow, K.,Wittmann, J.G.,Dierks, T.,von Figura, K.,Rudolph, M.G. A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme Proc.Natl.Acad.Sci.Usa, 103:81-86, 2006 Cited by PubMed: 16368756DOI: 10.1073/pnas.0507592102 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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