8JWD
 
 | | Histidine kinase QseE sensor domain of Escherichia coli O157:H7 | | Descriptor: | 1,2-ETHANEDIOL, histidine kinase | | Authors: | Matsumoto, K, Fukuda, Y, Inoue, T. | | Deposit date: | 2023-06-28 | | Release date: | 2023-11-15 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.33 Å) | | Cite: | Crystal structures of QseE and QseG: elements of a three-component system from Escherichia coli.
Acta Crystallogr.,Sect.F, 79, 2023
|
|
7X6H
 | |
7X6F
 | | Outer membrane lipoprotein QseG of Escherichia coli O157:H7 | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CITRATE ANION, ... | | Authors: | Matsumoto, K, Fukuda, Y, Inoue, T. | | Deposit date: | 2022-03-07 | | Release date: | 2023-03-15 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structures of QseE and QseG: elements of a three-component system from Escherichia coli.
Acta Crystallogr.,Sect.F, 79, 2023
|
|
7X6G
 | |
3AM9
 | | Complex of bovine xanthine dehydrogenase and trihydroxy FYX-051 | | Descriptor: | 4-[5-(2,6-dioxo-1,2,3,6-tetrahydropyridin-4-yl)-1H-1,2,4-triazol-3-yl]-6-oxo-1,6-dihydropyridine-2-carbonitrile, BICARBONATE ION, CALCIUM ION, ... | | Authors: | Matsumoto, K, Okamoto, K, Ashizawa, N, Matsumura, T, Kusano, T, Nishino, T. | | Deposit date: | 2010-08-18 | | Release date: | 2010-11-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | FYX-051: A Novel and Potent Hybrid-Type Inhibitor of Xanthine Oxidoreductase
J.Pharmacol.Exp.Ther., 336, 2011
|
|
2E27
 | | Crystal structure of Fv fragment of anti-ciguatoxin antibody complexed with ABC-ring of ciguatoxin | | Descriptor: | 3,7:6,10:9,14-TRIANHYDRO-2,5,11,12,13-PENTADEOXY-4-O-(METHOXYMETHYL)-L-ARABINO-L-ALLO-TETRADEC-12-ENONIC ACID, DIMETHYL SULFOXIDE, GLYCEROL, ... | | Authors: | Yokota, A, Tanaka, Y, Tsumoto, K. | | Deposit date: | 2006-11-08 | | Release date: | 2007-11-13 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Critical contribution of aromatic rings to specific recognition of polyether rings. The case of ciguatoxin CTX3C-ABC and its specific antibody 1C49.
J.Biol.Chem., 283, 2008
|
|
3ST7
 | | Crystal Structure of capsular polysaccharide assembling protein CapF from staphylococcus aureus | | Descriptor: | Capsular polysaccharide synthesis enzyme Cap5F, GLYCEROL, ZINC ION | | Authors: | Miyafusa, T, Tanaka, Y, Kuroda, M, Yao, M, Watanabe, M, Ohta, T, Tanaka, I, Caaveiro, J.M.M, Tsumoto, K. | | Deposit date: | 2011-07-09 | | Release date: | 2012-02-15 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Crystal structure of the enzyme CapF of Staphylococcus aureus reveals a unique architecture composed of two functional domains.
Biochem.J., 443, 2012
|
|
5X08
 | | Crystal structure of broadly neutralizing anti-HIV-1 antibody 4E10, mutant Npro, with peptide bound | | Descriptor: | ACETATE ION, CHLORIDE ION, Envelope glycoprotein gp160, ... | | Authors: | Caaveiro, J.M.M, Rujas, E, Nieva, J.L, Tsumoto, K. | | Deposit date: | 2017-01-20 | | Release date: | 2017-04-05 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Functional Contacts between MPER and the Anti-HIV-1 Broadly Neutralizing Antibody 4E10 Extend into the Core of the Membrane
J. Mol. Biol., 429, 2017
|
|
4WD4
 | | Crystal structure of human HO1 H25R | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Caaveiro, J.M.M, Morante, K, Sigala, P, Tsumoto, K. | | Deposit date: | 2014-09-06 | | Release date: | 2015-09-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | In-Cell Enzymology To Probe His-Heme Ligation in Heme Oxygenase Catalysis
Biochemistry, 55, 2016
|
|
4W4O
 | | High-resolution crystal structure of Fc bound to its human receptor Fc-gamma-RI | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, GLYCEROL, ... | | Authors: | Caaveiro, J.M.M, Kiyoshi, M, Tsumoto, K. | | Deposit date: | 2014-08-15 | | Release date: | 2015-04-29 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for binding of human IgG1 to its high-affinity human receptor Fc gamma RI
Nat Commun, 6, 2015
|
|
1IC4
 | | CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD32A)-HEN LYSOZYME COMPLEX | | Descriptor: | IGG1 FAB CHAIN H, LYSOZYME BINDING IG KAPPA CHAIN, LYSOZYME C | | Authors: | Shiroishi, M, Yokota, A, Tsumoto, K, Kondo, H, Nishimiya, Y, Horii, K, Matsushima, M, Ogasahara, K, Yutani, K, Kumagai, I. | | Deposit date: | 2001-03-30 | | Release date: | 2001-07-18 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction: the case of hen lysozyme-HyHEL-10 Fv complex.
J.Biol.Chem., 276, 2001
|
|
1IC7
 | | CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD32A99A)-HEN LYSOZYME COMPLEX | | Descriptor: | IGG1 FAB CHAIN H, LYSOZYME BINDING IG KAPPA CHAIN, LYSOZYME C | | Authors: | Shiroishi, M, Yokota, A, Tsumoto, K, Kondo, H, Nishimiya, Y, Horii, K, Matsushima, M, Ogasahara, K, Yutani, K, Kumagai, I. | | Deposit date: | 2001-03-30 | | Release date: | 2001-07-18 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction: the case of hen lysozyme-HyHEL-10 Fv complex.
J.Biol.Chem., 276, 2001
|
|
1IC5
 | | CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD99A)-HEN LYSOZYME COMPLEX | | Descriptor: | IGG1 FAB CHAIN H, LYSOZYME BINDING IG KAPPA CHAIN, LYSOZYME C | | Authors: | Shiroishi, M, Yokota, A, Tsumoto, K, Kondo, H, Nishimiya, Y, Horii, K, Matsushima, M, Ogasahara, K, Yutani, K, Kumagai, I. | | Deposit date: | 2001-03-30 | | Release date: | 2001-07-18 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction: the case of hen lysozyme-HyHEL-10 Fv complex.
J.Biol.Chem., 276, 2001
|
|
8YX1
 | | CD40 in complex with Bleselumab Fab | | Descriptor: | Bleselumab, heavy chain, light chain, ... | | Authors: | Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K. | | Deposit date: | 2024-04-01 | | Release date: | 2024-05-08 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structures of human CD40 in complex with monoclonal antibodies dacetuzumab and bleselumab.
Biochem.Biophys.Res.Commun., 714, 2024
|
|
8YX9
 | | CD40 in complex with Dacetuzumab Fab | | Descriptor: | Dacetuzumab, Heavy chain, light chain, ... | | Authors: | Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K. | | Deposit date: | 2024-04-02 | | Release date: | 2024-05-08 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structures of human CD40 in complex with monoclonal antibodies dacetuzumab and bleselumab.
Biochem.Biophys.Res.Commun., 714, 2024
|
|
4YRD
 | | Crystal structure of CapF with inhibitor 3-isopropenyl-tropolone | | Descriptor: | 2-hydroxy-3-(prop-1-en-2-yl)cyclohepta-2,4,6-trien-1-one, Capsular polysaccharide synthesis enzyme Cap5F, ZINC ION | | Authors: | Nakano, K, Chigira, T, Miyafusa, T, Nagatoishi, S, Caaveiro, J.M.M, Tsumoto, K. | | Deposit date: | 2015-03-15 | | Release date: | 2015-10-21 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | Discovery and characterization of natural tropolones as inhibitors of the antibacterial target CapF from Staphylococcus aureus.
Sci Rep, 5, 2015
|
|
4TSN
 | | Crystal structure of FraC with POC bound (crystal form II) | | Descriptor: | ACETATE ION, Fragaceatoxin C, GLYCEROL, ... | | Authors: | Caaveiro, J.M.M, Tanaka, K, Tsumoto, K. | | Deposit date: | 2014-06-19 | | Release date: | 2015-03-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
|
|
4TSQ
 | | Crystal structure of FraC with DHPC bound (crystal form III) | | Descriptor: | 1,2-dihexanoyl-sn-glycero-3-phosphocholine, CHLORIDE ION, Fragaceatoxin C, ... | | Authors: | Caaveiro, J.M.M, Tanaka, K, Tsumoto, K. | | Deposit date: | 2014-06-19 | | Release date: | 2015-03-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
|
|
7WKI
 | |
4TSO
 | | Crystal structure of FraC with DHPC bound (crystal form I) | | Descriptor: | 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Fragaceatoxin C, PHOSPHATE ION, ... | | Authors: | Caaveiro, J.M.M, Tanaka, K, Tsumoto, K. | | Deposit date: | 2014-06-19 | | Release date: | 2015-03-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
|
|
4TSP
 | | Crystal structure of FraC with DHPC bound (crystal form II) | | Descriptor: | 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Fragaceatoxin C, PHOSPHATE ION, ... | | Authors: | Caaveiro, J.M.M, Tanaka, K, Tsumoto, K. | | Deposit date: | 2014-06-19 | | Release date: | 2015-03-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
|
|
4TSY
 | | Crystal structure of FraC with lipids | | Descriptor: | 2-[[(E,2S,3R)-2-(hexanoylamino)-3-oxidanyl-dec-4-enoxy]-oxidanyl-phosphoryl]oxyethyl-trimethyl-azanium, Fragaceatoxin C, HEPTANE-1,2,3-TRIOL, ... | | Authors: | Caaveiro, J.M.M, Tanaka, K, Tsumoto, K. | | Deposit date: | 2014-06-19 | | Release date: | 2015-03-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.14 Å) | | Cite: | Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
|
|
4TSL
 | | Crystal structure of FraC with POC bound (crystal form I) | | Descriptor: | ACETATE ION, FORMIC ACID, Fragaceatoxin C, ... | | Authors: | Caaveiro, J.M.M, Tanaka, K, Tsumoto, K. | | Deposit date: | 2014-06-19 | | Release date: | 2015-03-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
|
|
5GWF
 | | FraC with GlcNAc(6S) bound | | Descriptor: | 2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose, CHLORIDE ION, DELTA-actitoxin-Afr1a, ... | | Authors: | Caaveiro, J.M.M, Tsumoto, K. | | Deposit date: | 2016-09-11 | | Release date: | 2017-06-21 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Haemolytic actinoporins interact with carbohydrates using their lipid-binding module
Philos. Trans. R. Soc. Lond., B, Biol. Sci., 372, 2017
|
|
5GHW
 | | Crystal structure of broad neutralizing antibody 10E8 with long epitope bound | | Descriptor: | Endogenous retrovirus group K member 8 Env polyprotein, FAB 10E8 HEAVY CHAIN, FAB 10E8 LIGHT CHAIN, ... | | Authors: | Caaveiro, J.M.M, Rujas, E, Morante, K, Nieva, J.L, Tsumoto, K. | | Deposit date: | 2016-06-21 | | Release date: | 2016-11-23 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface
Sci Rep, 6, 2016
|
|
