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4WD4

Crystal structure of human HO1 H25R

Summary for 4WD4
Entry DOI10.2210/pdb4wd4/pdb
DescriptorHeme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
Functional Keywordsheme oxygenase, proximal histidine, heme coordination, site-directed mutagenesis, biliverdin biosensor, oxidoreductase
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total formula weight136114.85
Authors
Caaveiro, J.M.M.,Morante, K.,Sigala, P.,Tsumoto, K. (deposition date: 2014-09-06, release date: 2015-09-09, Last modification date: 2023-11-08)
Primary citationSigala, P.A.,Morante, K.,Tsumoto, K.,Caaveiro, J.M.,Goldberg, D.E.
In-Cell Enzymology To Probe His-Heme Ligation in Heme Oxygenase Catalysis
Biochemistry, 55:4836-4849, 2016
Cited by
PubMed: 27490825
DOI: 10.1021/acs.biochem.6b00562
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.95 Å)
Structure validation

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