4W4O

High-resolution crystal structure of Fc bound to its human receptor Fc-gamma-RI

Summary for 4W4O

• Entry DOI: 10.2210/pdb4w4o/pdb
• Related: 4W4N
• Descriptor: Ig gamma-1 chain C region, High affinity immunoglobulin gamma Fc receptor I, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: immune complex igg1 protein-protein complex asymmetry, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 87850.19

Authors

Caaveiro, J.M.M.,Kiyoshi, M.,Tsumoto, K. (deposition date: 2014-08-15, release date: 2015-04-29, Last modification date: 2023-11-08)

• Primary citation: Kiyoshi, M.,Caaveiro, J.M.M.,Kawai, T.,Tashiro, S.,Ide, T.,Asaoka, Y.,Hatayama, K.,Tsumoto, K.; Structural basis for binding of human IgG1 to its high-affinity human receptor Fc gamma RI; Nat Commun, 6:6866-6866, 2015; PubMed: 25925696; DOI: 10.1038/ncomms7866

Experimental method

X-RAY DIFFRACTION (1.8 Å)