2KDI
| Solution structure of a Ubiquitin/UIM fusion protein | 分子名称: | Ubiquitin, Vacuolar protein sorting-associated protein 27 fusion protein | 著者 | Sgourakis, N.G, Patel, M.M, Garcia, A.E, Makhatadze, G.I, McCallum, S.A. | 登録日 | 2009-01-09 | 公開日 | 2010-02-09 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformational Dynamics and Structural Plasticity Play Critical Roles in the Ubiquitin Recognition of a UIM Domain. J.Mol.Biol., 396, 2010
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2MPZ
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2MIZ
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3J1X
| A refined model of the prototypical Salmonella typhimurium T3SS basal body reveals the molecular basis for its assembly | 分子名称: | Protein PrgH | 著者 | Sgourakis, N.G, Bergeron, J.R.C, Worrall, L.J, Strynadka, N.C.J, Baker, D. | 登録日 | 2012-07-10 | 公開日 | 2013-05-22 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (11.7 Å) | 主引用文献 | A Refined Model of the Prototypical Salmonella SPI-1 T3SS Basal Body Reveals the Molecular Basis for Its Assembly. Plos Pathog., 9, 2013
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3J1V
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3J1W
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8ERX
| Structure of chimeric HLA-A*11:01-A*02:01 bound to HIV-1 RT peptide | 分子名称: | Beta-2-microglobulin, HIV-1 RT, HLA-A*02:01 | 著者 | Florio, T.J, Ani, O, Young, M.C, Mallik, L, Sgourakis, N.G. | 登録日 | 2022-10-13 | 公開日 | 2023-01-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules. Front Immunol, 14, 2023
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8SBL
| Structure of HLA-A*24:02 in complex with peptide, LYLPVRVLI | 分子名称: | Beta-2-microglobulin, LEU-TYR-LEU-PRO-VAL-ARG-VAL-LEU-ILE, MHC class I antigen | 著者 | Mallik, L, Young, M.C, Sgourakis, N.G. | 登録日 | 2023-04-03 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion. Sci Immunol, 8, 2023
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8SBK
| Structure of HLA-A*24:02 in complex with peptide, LYLPVRVLI (ATG2A). | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, LEU-TYR-LEU-PRO-VAL-ARG-VAL-LEU-ILE, ... | 著者 | Mallik, L, Young, M.C, Sgourakis, N.G. | 登録日 | 2023-04-03 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion. Sci Immunol, 8, 2023
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6AT9
| Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-A*0101 | 分子名称: | ALK, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G. | 登録日 | 2017-08-28 | 公開日 | 2018-03-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.9503 Å) | 主引用文献 | A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations. Front Immunol, 9, 2018
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6MPP
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8EK5
| Engineered scFv 10LH bound to PHOX2B/HLA-A24:02 | 分子名称: | 10LH single chain fragment variable (scFv), Beta-2-microglobulin, GLYCEROL, ... | 著者 | Garfinkle, S.E, Florio, T.J, Sgourakis, N.G. | 登録日 | 2022-09-20 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion. Sci Immunol, 8, 2023
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8ESH
| Structure of chimeric HLA-A*02:01 bound to CMV peptide | 分子名称: | Beta-2-microglobulin, CMV peptide, HLA-A*02:01 | 著者 | Florio, T.J, Ani, O, Young, M.C, Mallik, L, Sgourakis, N.G. | 登録日 | 2022-10-14 | 公開日 | 2023-01-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules. Front Immunol, 14, 2023
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5TXS
| Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-15 alpha chain, ... | 著者 | Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G. | 登録日 | 2016-11-17 | 公開日 | 2017-11-29 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.697 Å) | 主引用文献 | A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations. Front Immunol, 9, 2018
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5VZ5
| Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501 | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | 著者 | Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G. | 登録日 | 2017-05-26 | 公開日 | 2018-03-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5901 Å) | 主引用文献 | A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations. Front Immunol, 9, 2018
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5WOX
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5WOZ
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5WOT
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5WOY
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7RNO
| Model of the Ac-6-FP/hpMR1/bB2m/TAPBPR complex from integrated docking, NMR and restrained MD | 分子名称: | Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, N-(6-formyl-4-oxo-3,4-dihydropteridin-2-yl)acetamide, ... | 著者 | McShan, A.C, Sgourakis, N.G. | 登録日 | 2021-07-29 | 公開日 | 2022-05-11 | 最終更新日 | 2022-08-10 | 実験手法 | SOLUTION NMR | 主引用文献 | TAPBPR employs a ligand-independent docking mechanism to chaperone MR1 molecules. Nat.Chem.Biol., 18, 2022
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6DMP
| De Novo Design of a Protein Heterodimer with Specificity Mediated by Hydrogen Bond Networks | 分子名称: | Designed orthogonal protein DHD13_XAAA_A, Designed orthogonal protein DHD13_XAAA_B | 著者 | Chen, Z, Flores-Solis, D, Sgourakis, N.G, Baker, D. | 登録日 | 2018-06-05 | 公開日 | 2018-12-19 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Programmable design of orthogonal protein heterodimers. Nature, 565, 2019
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7MJ9
| HLA-A*02:01 bound to Neuroblastoma Derived mutant IGFBPL1 peptide | 分子名称: | Beta-2-microglobulin, Insulin-like growth factor-binding protein-like 1 altered peptide, MHC class I antigen | 著者 | Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G. | 登録日 | 2021-04-19 | 公開日 | 2021-08-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs. Nature, 599, 2021
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7MJ6
| HLA-A*02:01 bound to Neuroblastoma Derived IGFBPL1 peptide | 分子名称: | Beta-2-microglobulin, GLYCEROL, Insulin-like growth factor-binding protein-like 1 peptide, ... | 著者 | Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G. | 登録日 | 2021-04-19 | 公開日 | 2021-08-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs. Nature, 599, 2021
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7MJ8
| HLA-A*02:01 bound to Neuroblastoma Derived IGFBPL1 peptide | 分子名称: | Beta-2-microglobulin, GLYCEROL, Insulin-like growth factor-binding protein-like 1 peptide, ... | 著者 | Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G. | 登録日 | 2021-04-19 | 公開日 | 2021-08-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs. Nature, 599, 2021
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7MJ7
| HLA-A*02:01 bound to Neuroblastoma Derived IGFBPL1 peptide | 分子名称: | Beta-2-microglobulin, GLYCEROL, Insulin-like growth factor-binding protein-like 1 peptide, ... | 著者 | Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G. | 登録日 | 2021-04-19 | 公開日 | 2021-08-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs. Nature, 599, 2021
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