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8GKG
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BU of 8gkg by Molmil
Human TRPV3 pentamer structure
分子名称: Transient receptor potential cation channel subfamily V member 3
著者Lansky, S, Betancourt, J.M, Scheuring, S.
登録日2023-03-18
公開日2023-09-06
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (4.38 Å)
主引用文献A pentameric TRPV3 channel with a dilated pore.
Nature, 621, 2023
8GKA
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Human TRPV3 tetramer structure, closed conformation
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Lansky, S, Betancourt, J.M, Scheuring, S.
登録日2023-03-17
公開日2023-09-06
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (2.55 Å)
主引用文献A pentameric TRPV3 channel with a dilated pore.
Nature, 621, 2023
4CHW
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The electron crystallography structure of the cAMP-free potassium channel MloK1
分子名称: CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNEL MLL3241, POTASSIUM ION
著者Kowal, J, Chami, M, Baumgartner, P, Arheit, M, Chiu, P.L, Rangl, M, Scheuring, S, Schroeder, G.F, Nimigean, C.M, Stahlberg, H.
登録日2013-12-04
公開日2014-01-15
最終更新日2019-04-24
実験手法ELECTRON CRYSTALLOGRAPHY (7 Å)
主引用文献Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1.
Nat Commun, 5, 2014
4CHV
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The electron crystallography structure of the cAMP-bound potassium channel MloK1
分子名称: CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNEL MLL3241, POTASSIUM ION
著者Kowal, J, Chami, M, Baumgartner, P, Arheit, M, Chiu, P.L, Rangl, M, Scheuring, S, Schroeder, G.F, Nimigean, C.M, Stahlberg, H.
登録日2013-12-04
公開日2014-01-15
最終更新日2019-04-24
実験手法ELECTRON CRYSTALLOGRAPHY (7 Å)
主引用文献Ligand-Induced Structural Changes in the Cyclic Nucleotide-Modulated Potassium Channel Mlok1
Nat.Commun., 5, 2014
6SB1
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Crystal structure of murine perforin-2 P2 domain crystal form 1
分子名称: CHLORIDE ION, GLYCEROL, Macrophage-expressed gene 1 protein
著者Ni, T, Ginger, L, Gilbert, R.J.C.
登録日2019-07-18
公開日2020-02-05
最終更新日2020-02-26
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity.
Sci Adv, 6, 2020
6SB3
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CryoEM structure of murine perforin-2 ectodomain in a pre-pore form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
著者Ni, T, Yu, X, Gilbert, R.J.C.
登録日2019-07-18
公開日2020-02-05
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity.
Sci Adv, 6, 2020
6SB4
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Crystal structure of murine perforin-2 P2 domain crystal form 2
分子名称: Macrophage-expressed gene 1 protein
著者Ni, T, Yu, X, Ginger, L, Gilbert, R.J.C.
登録日2019-07-18
公開日2020-02-05
最終更新日2020-02-26
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity.
Sci Adv, 6, 2020
6SB5
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CryoEM structure of murine perforin-2 ectodomain in a pore form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
著者Ni, T, Yu, X, Gilbert, R.J.C.
登録日2019-07-18
公開日2020-02-05
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity.
Sci Adv, 6, 2020
7RXB
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afTMEM16 lipid scramblase in C18 lipid nanodiscs in the absence of Ca2+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, afTMEM16 lipid scramblase
著者Feng, Z, Accardi, A.
登録日2021-08-22
公開日2022-05-18
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RXA
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afTMEM16 DE/AA mutant in C14 lipid nanodiscs in the presence of Ca2+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, afTMEM16 lipid scramblase
著者Feng, Z, Accardi, A.
登録日2021-08-22
公開日2022-05-18
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RX2
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afTMEM16 in C22 lipid nanodiscs with MSP1E3 scaffold protein in the presnece of Ca2+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, afTMEM16 lipid scramblase
著者Falzone, M.E, Accardi, A.
登録日2021-08-21
公開日2022-05-18
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RWJ
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afTMEM16 in C22 lipid nanodiscs with MSP2N2 scaffold protein in the presnece of Ca2+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Plasma membrane channel protein (Aqy1), ...
著者Falzone, M.E, Accardi, A.
登録日2021-08-20
公開日2022-05-18
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RXG
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afTMEM16 in C18 lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+, full dimer
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, afTMEM16 lipid scramblase
著者Falzone, M.E, Accardi, A.
登録日2021-08-23
公開日2022-05-18
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (2.28 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RX3
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afTMEM16 in C14 lipid nanodiscs with MSP1E3 scaffold protein in the absence of Ca2+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, afTMEM16 lipid scramblase
著者Falzone, M.E, Accardi, A.
登録日2021-08-21
公開日2022-05-18
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RXH
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afTMEM16 in C18 lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+, monomer with extra lipids
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, afTMEM16 lipid scramblase
著者Falzone, M.E, Accardi, A.
登録日2021-08-23
公開日2022-05-18
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022

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件を2024-04-24に公開中

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