6SB4

Crystal structure of murine perforin-2 P2 domain crystal form 2

Summary for 6SB4

Entry DOI	10.2210/pdb6sb4/pdb
Descriptor	Macrophage-expressed gene 1 protein (1 entity in total)
Functional Keywords	pore-forming protein, p2 domain, membrane binding, beta-hairpin, toxin
Biological source	Mus musculus (Mouse)
Total number of polymer chains	8
Total formula weight	258365.00
Authors	Ni, T.,Yu, X.,Ginger, L.,Gilbert, R.J.C. (deposition date: 2019-07-18, release date: 2020-02-05, Last modification date: 2020-02-26)
Primary citation	Ni, T.,Jiao, F.,Yu, X.,Aden, S.,Ginger, L.,Williams, S.I.,Bai, F.,Prazak, V.,Karia, D.,Stansfeld, P.,Zhang, P.,Munson, G.,Anderluh, G.,Scheuring, S.,Gilbert, R.J.C. Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity. Sci Adv, 6:eaax8286-eaax8286, 2020 Cited by PubMed: 32064340 DOI: 10.1126/sciadv.aax8286 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.17 Å)

Structure validation