7KFL
 
 | | Crystal structure of the cargo-binding domain from the plant class XI myosin (MyoXIk) | | 分子名称: | Myosin-17 | | 著者 | Turowski, V.R, Ruiz, D.M, Nascimento, A.F.Z, Millan, C, Sammito, M.D, Juanhuix, J, Cremonesi, A.S, Uson, I, Giuseppe, P.O, Murakami, M.T. | | 登録日 | 2020-10-14 | | 公開日 | 2021-04-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure of the class XI myosin globular tail reveals evolutionary hallmarks for cargo recognition in plants.
Acta Crystallogr D Struct Biol, 77, 2021
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6GS3
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4GDO
 | | Structure of a fragment of the rod domain of plectin | | 分子名称: | Plectin | | 著者 | De Pereda, J.M, Buey, R.M, Uson, I, Sammito, M.D, De Marino, I. | | 登録日 | 2012-08-01 | | 公開日 | 2013-09-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Exploiting tertiary structure through local folds for crystallographic phasing.
Nat.Methods, 10, 2013
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8XWX
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8TJG
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8TUA
 | | Full-length P-Rex1 in complex with inositol 1,3,4,5-tetrakisphosphate (IP4) | | 分子名称: | INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein | | 著者 | Cash, J.N, Tesmer, J.J.G. | | 登録日 | 2023-08-15 | | 公開日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Full-length P-Rex1 in complex with inositol 1,3,4,5-tetrakisphosphate (IP4)
Elife, 2024
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8SP7
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8G8F
 | | Human IMPDH2 mutant - L245P, treated with ATP, IMP, and NAD+; extended filament segment reconstruction | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, ... | | 著者 | O'Neill, A.G, Kollman, J.M. | | 登録日 | 2023-02-17 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-08-09 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J.Biol.Chem., 299, 2023
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8G9B
 | | Human IMPDH2 mutant - L245P, treated with GTP, ATP, IMP, and NAD+; compressed filament segment reconstruction | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... | | 著者 | O'Neill, A.G, Kollman, J.M. | | 登録日 | 2023-02-21 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-08-09 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J.Biol.Chem., 299, 2023
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8FSD
 | | P130R mutant of soybean SHMT8 in complex with PLP-glycine and formylTHF | | 分子名称: | 1,2-ETHANEDIOL, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, ... | | 著者 | Beamer, L.J, Korasick, D.A. | | 登録日 | 2023-01-09 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Structural and functional analysis of two SHMT8 variants associated with soybean cyst nematode resistance.
Febs J., 291, 2024
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8CGA
 | | Structure of Mycobacterium tuberculosis dUTPase delta 133A-137S mutant | | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | | 著者 | Toth, Z.S, Benedek, A, Leveles, I, Vertessy, B.G. | | 登録日 | 2023-02-03 | | 公開日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structure of Mycobacterium tuberculosis dUTPase delta 133A-137S mutant
To Be Published
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7BBM
 | | Mutant nitrobindin M75L/H76L/Q96C/M148L (NB4H) from Arabidopsis thaliana with cofactor MnPPIX | | 分子名称: | 1,2-ETHANEDIOL, MANGANESE PROTOPORPHYRIN IX, UPF0678 fatty acid-binding protein-like protein At1g79260 | | 著者 | Minges, A, Sauer, D.F, Wittwer, M, Markel, U, Spiertz, M, Schiffels, J, Davari, M.D, Okuda, J, Schwaneberg, U, Groth, G. | | 登録日 | 2020-12-18 | | 公開日 | 2021-05-26 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | | 主引用文献 | Chemogenetic engineering of nitrobindin toward an artificial epoxygenase
Catalysis Science And Technology, 2021
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7JY2
 | | Z-DNA joint X-ray/Neutron | | 分子名称: | Chains: A,B | | 著者 | Harp, J.M, Coates, L, Egli, M. | | 登録日 | 2020-08-28 | | 公開日 | 2021-04-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | NEUTRON DIFFRACTION (1.5 Å), X-RAY DIFFRACTION | | 主引用文献 | Water structure around a left-handed Z-DNA fragment analyzed by cryo neutron crystallography.
Nucleic Acids Res., 49, 2021
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7KWO
 | | rFVIIIFc-VWF-XTEN (BIVV001) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COPPER (II) ION, ... | | 著者 | Fuller, J.R, Batchelor, J.D. | | 登録日 | 2020-12-01 | | 公開日 | 2021-03-03 | | 最終更新日 | 2021-06-09 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Molecular determinants of the factor VIII/von Willebrand factor complex revealed by BIVV001 cryo-electron microscopy.
Blood, 137, 2021
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7LM4
 | | The crystal structure of the I38T mutant PA Endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988503 | | 分子名称: | 5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-2-(2-methylphenyl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... | | 著者 | Cuypers, M.G, Slavish, P.J, Jayaraman, S, Rankovic, Z, White, S.W. | | 登録日 | 2021-02-05 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential.
Eur.J.Med.Chem., 247, 2023
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7ZFM
 | | Engineered Protein Targeting the Zika Viral Envelope Fusion Loop | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, HEXAETHYLENE GLYCOL, ... | | 著者 | Athayde, D, Archer, M, Viana, I.F.T, Adan, W.C.S, Xavier, L.S.S, Lins, R.D. | | 登録日 | 2022-04-01 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.711 Å) | | 主引用文献 | In Vitro Neutralisation of Zika Virus by an Engineered Protein Targeting the Viral Envelope Fusion Loop
SSRN, 2022
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8BHD
 | | N-terminal domain of Plasmodium berghei glutamyl-tRNA synthetase (Tbxo4 derivative crystal structure) | | 分子名称: | GLYCEROL, Glutamate--tRNA ligase, SULFATE ION, ... | | 著者 | Benas, P, Jaramillo Ponce, J.R, Legrand, P, Frugier, M, Sauter, C. | | 登録日 | 2022-10-31 | | 公開日 | 2023-01-25 | | 最終更新日 | 2023-02-08 | | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | | 主引用文献 | Solution X-ray scattering highlights discrepancies in Plasmodium multi-aminoacyl-tRNA synthetase complexes.
Protein Sci., 32, 2023
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7OS2
 | | Cryo-EM structure of Brr2 in complex with Jab1/MPN and C9ORF78 | | 分子名称: | Pre-mRNA-processing-splicing factor 8, Telomere length and silencing protein 1 homolog, U5 small nuclear ribonucleoprotein 200 kDa helicase | | 著者 | Bergfort, A, Hilal, T, Weber, G, Wahl, M.C. | | 登録日 | 2021-06-07 | | 公開日 | 2022-02-23 | | 最終更新日 | 2022-03-30 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
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7OS1
 | | Cryo-EM structure of Brr2 in complex with Fbp21 | | 分子名称: | U5 small nuclear ribonucleoprotein 200 kDa helicase, WW domain-binding protein 4 | | 著者 | Bergfort, A, Hilal, T, Weber, G, Wahl, M.C. | | 登録日 | 2021-06-07 | | 公開日 | 2022-02-23 | | 最終更新日 | 2022-03-30 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
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7PTH
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7PV9
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7PPL
 | | SHP2 catalytic domain in complex with IRS1 (625-639) phosphopeptide (pTyr-632, pSer-636) | | 分子名称: | ETHANOL, GLYCEROL, Insulin receptor substrate 1, ... | | 著者 | Sok, P, Zeke, A, Remenyi, A. | | 登録日 | 2021-09-14 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Structural insights into the pSer/pThr dependent regulation of the SHP2 tyrosine phosphatase in insulin and CD28 signaling.
Nat Commun, 13, 2022
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7PPM
 | | SHP2 catalytic domain in complex with IRS1 (889-901) phosphopeptide (pSer-892, pTyr-896) | | 分子名称: | GLYCEROL, Insulin receptor substrate 1, Tyrosine-protein phosphatase non-receptor type 11,Tyrosine-protein phosphatase non-receptor type 11 | | 著者 | Sok, P, Zeke, A, Remenyi, A. | | 登録日 | 2021-09-14 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Structural insights into the pSer/pThr dependent regulation of the SHP2 tyrosine phosphatase in insulin and CD28 signaling.
Nat Commun, 13, 2022
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7PPN
 | | SHP2 catalytic domain in complex with CD28 (183-198) phosphopeptide (pTyr-191, p-Thr-195) | | 分子名称: | GLYCEROL, T-cell-specific surface glycoprotein CD28, Tyrosine-protein phosphatase non-receptor type 11,Tyrosine-protein phosphatase non-receptor type 11 | | 著者 | Sok, P, Zeke, A, Remenyi, A. | | 登録日 | 2021-09-14 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural insights into the pSer/pThr dependent regulation of the SHP2 tyrosine phosphatase in insulin and CD28 signaling.
Nat Commun, 13, 2022
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7U6K
 | | Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence. | | 分子名称: | DNA (5'-D(A*CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*G)-3'), DNA (5'-D(A*GP*GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*G)-3'), MAGNESIUM ION, ... | | 著者 | Ward, A.R, Snow, C.D. | | 登録日 | 2022-03-04 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Modular Protein-DNA Cocrystals as Precise, Programmable Assembly Scaffolds.
Acs Nano, 17, 2023
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