8TUA

Full-length P-Rex1 in complex with inositol 1,3,4,5-tetrakisphosphate (IP4)

Summary for 8TUA

• Entry DOI: 10.2210/pdb8tua/pdb
• EMDB information: 41621
• Descriptor: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE (2 entities in total)
• Functional Keywords: rho guanine-nucleotide exchange factor, dbl homology domain, pleckstrin homology domain, phosphatidylinositol 3, 4, 5-trisphosphate binding, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 183959.56

Authors

Cash, J.N.,Tesmer, J.J.G. (deposition date: 2023-08-15, release date: 2024-04-10)

• Primary citation: Ravala, S.K.,Adame-Garcia, S.R.,Li, S.,Chen, C.,Cianfrocco, M.A.,Gutkind, J.S.,Cash, J.N.,Tesmer, J.J.G.; Full-length P-Rex1 in complex with inositol 1,3,4,5-tetrakisphosphate (IP4); Elife, 2024; DOI: 10.7554/eLife.92822.1

Experimental method

ELECTRON MICROSCOPY (4.1 Å)