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2FNB
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BU of 2fnb by Molmil
NMR STRUCTURE OF THE FIBRONECTIN ED-B DOMAIN, NMR, 20 STRUCTURES
Descriptor: PROTEIN (FIBRONECTIN)
Authors:Fattorusso, R, Pellecchia, M, Viti, F, Neri, P, Neri, D, Wuthrich, K.
Deposit date:1998-12-16
Release date:1998-12-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:NMR structure of the human oncofoetal fibronectin ED-B domain, a specific marker for angiogenesis.
Structure Fold.Des., 7, 1999
8P7G
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BU of 8p7g by Molmil
Structural characterization of PHOX2B and its DNA interactions shed lights into the molecular basis of the + 7Ala variant pathogenicity in CCHS
Descriptor: Paired mesoderm homeobox protein 2B
Authors:Russo, L, Diana, D, Fattorusso, R.
Deposit date:2023-05-30
Release date:2024-05-15
Last modified:2024-06-26
Method:SOLUTION NMR
Cite:Structural characterization of PHOX2B and its DNA interaction shed light on the molecular basis of the +7Ala variant pathogenicity in CCHS.
Chem Sci, 15, 2024
2MLG
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BU of 2mlg by Molmil
Stf76 from the Sulfolobus islandicus plasmid-virus pSSVx
Descriptor: Sulfolobus transcription factor 76 aminoacid protein, Stf76
Authors:Farina, B, Russo, L, Fattorusso, R.
Deposit date:2014-02-27
Release date:2014-03-12
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural and functional studies of Stf76 from the Sulfolobus islandicus plasmid-virus pSSVx: a novel peculiar member of the winged helix-turn-helix transcription factor family.
Nucleic Acids Res., 42, 2014
2LQY
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BU of 2lqy by Molmil
Structure and orientation of the gH625-644 membrane interacting region of herpes simplex virus type 1 in a membrane mimetic system.
Descriptor: Envelope glycoprotein H
Authors:Isernia, C, Galdiero, S, Russo, L, Falanga, A, Cantisani, M, Vitiello, M, Fattorusso, R, Malgieri, G, Galdiero, M.
Deposit date:2012-03-19
Release date:2012-04-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure and Orientation of the gH625-644 Membrane Interacting Region of Herpes Simplex Virus Type 1 in a Membrane Mimetic System.
Biochemistry, 51, 2012
2J14
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BU of 2j14 by Molmil
3,4,5-Trisubstituted Isoxazoles as Novel PPARdelta Agonists: Part2
Descriptor: (3-{4-[2-(2,4-DICHLORO-PHENOXY)-ETHYLCARBAMOYL]-5-PHENYL-ISOXAZOL-3-YL}-PHENYL)-ACETIC ACID, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA
Authors:Epple, R, Azimioara, M, Russo, R, Xie, Y, Wang, X, Cow, C, Wityak, J, Karanewsky, D, Bursulaya, B, Kreusch, A, Tuntland, T, Gerken, A, Iskandar, M, Saez, E, Seidel, H.M, Tian, S.S.
Deposit date:2006-08-08
Release date:2006-09-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:3,4,5-Trisubstituted Isoxazoles as Novel Ppardelta Agonists. Part 2
Bioorg.Med.Chem.Lett., 16, 2006
2L1O
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BU of 2l1o by Molmil
Zinc to cadmium replacement in the A. thaliana SUPERMAN Cys2His2 zinc finger induces structural rearrangements of typical DNA base determinant positions
Descriptor: CADMIUM ION, Transcriptional regulator SUPERMAN
Authors:Malgieri, G, Zaccaro, L, Leone, M, Bucci, E, Esposito, S, Baglivo, I, Del Gatto, A, Scandurra, R, Pedone, P.V, Fattorusso, R, Isernia, C.
Deposit date:2010-07-31
Release date:2011-06-08
Last modified:2011-12-21
Method:SOLUTION NMR
Cite:Zinc to cadmium replacement in the A. thaliana SUPERMAN Cys(2) His(2) zinc finger induces structural rearrangements of typical DNA base determinant positions.
Biopolymers, 95, 2011
5MTL
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BU of 5mtl by Molmil
Crystal structure of an amyloidogenic light chain
Descriptor: light chain dimer,IGL@ protein,IGL@ protein
Authors:Oberti, L, Rognoni, P, Russo, R, Bacarizo, J, Bolognesi, M, Ricagno, S.
Deposit date:2017-01-10
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5MUH
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BU of 5muh by Molmil
Crystal structure of an amyloidogenic light chain dimer H7
Descriptor: light chain dimer
Authors:Oberti, L, Rognoni, P, Russo, R, Maritan, M, Bacarizo, J, Bolognesi, M, Ricagno, S.
Deposit date:2017-01-13
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5M6I
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BU of 5m6i by Molmil
Crystal structure of non-cardiotoxic Bence-Jones light chain dimer M8
Descriptor: SODIUM ION, light chain dimer
Authors:Oberti, L, Rognoni, P, Russo, R, Bacarizo, J, Bolognesi, M, Ricagno, S.
Deposit date:2016-10-25
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
1NJQ
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BU of 1njq by Molmil
NMR structure of the single QALGGH zinc finger domain from Arabidopsis thaliana SUPERMAN protein
Descriptor: ZINC ION, superman protein
Authors:Isernia, C, Bucci, E, Leone, M, Zaccaro, L, Di Lello, P, Digilio, G, Esposito, S, Saviano, M, Di Blasio, B, Pedone, C, Pedone, P.V, Fattorusso, R.
Deposit date:2003-01-02
Release date:2003-03-04
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:NMR Structure of the Single QALGGH Zinc Finger Domain from the Arabidopsis thaliana SUPERMAN Protein.
Chembiochem, 4, 2003
6S0N
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BU of 6s0n by Molmil
A9 peptide derived from Herceptin fab binding region
Descriptor: GLN-ASP-VAL-ASN-THR-ALA-VAL-ALA-TRP
Authors:De Luca, S, Verdoliva, V, Saviano, M, Fattorusso, R, Diana, D.
Deposit date:2019-06-17
Release date:2019-11-06
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:SPR and NMR characterization of the molecular interaction between A9 peptide and a model system of HER2 receptor: A fragment approach for selecting peptide structures specific for their target.
J.Pept.Sci., 26, 2020
1RQM
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BU of 1rqm by Molmil
SOLUTION STRUCTURE OF THE K18G/R82E ALICYCLOBACILLUS ACIDOCALDARIUS THIOREDOXIN MUTANT
Descriptor: Thioredoxin
Authors:Leone, M, Di Lello, P, Ohlenschlager, O, Pedone, E.M, Bartolucci, S, Rossi, M, Di Blasio, B, Pedone, C, Saviano, M, Isernia, C, Fattorusso, R.
Deposit date:2003-12-05
Release date:2004-06-22
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Solution Structure and Backbone Dynamics of the K18G/R82E Alicyclobacillus acidocaldarius Thioredoxin Mutant: A Molecular Analysis of Its Reduced Thermal Stability.
Biochemistry, 43, 2004
5W2P
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BU of 5w2p by Molmil
Crystal structure of Mycobacterium tuberculosis KasA in complex with 6U5
Descriptor: 3,3',3''-phosphanetriyltripropanoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 1, GLYCEROL, ...
Authors:Capodagli, G.C, Neiditch, M.B.
Deposit date:2017-06-06
Release date:2018-12-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA.
MBio, 9, 2018
6Z3X
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BU of 6z3x by Molmil
Crystal structure of the designed antibody DesAb-anti-HSA-P1
Descriptor: CACODYLATE ION, DesAb-anti-HSA-P1, IMIDAZOLE, ...
Authors:Costanzi, E, Sormanni, P, Ricagno, S.
Deposit date:2020-05-22
Release date:2021-03-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Fragment-based computational design of antibodies targeting structured epitopes.
Sci Adv, 8, 2022
5W2Q
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BU of 5w2q by Molmil
Crystal structure of Mycobacterium tuberculosis KasA in complex with 6U5
Descriptor: 3,3',3''-phosphanetriyltripropanoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 1, GLYCEROL, ...
Authors:Capodagli, G.C, Neiditch, M.B.
Deposit date:2017-06-06
Release date:2018-12-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA.
MBio, 9, 2018
5W2O
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BU of 5w2o by Molmil
Crystal structure of Mycobacterium tuberculosis KasA
Descriptor: 3,3',3''-phosphanetriyltripropanoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 1, CHLORIDE ION, ...
Authors:Capodagli, G.C, Neiditch, M.B.
Deposit date:2017-06-06
Release date:2018-12-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA.
MBio, 9, 2018
5W2S
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BU of 5w2s by Molmil
Crystal Structure of Mycobacterium Tuberculosis KasA in complex with KMG
Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 1, GLYCEROL, ISOPROPYL ALCOHOL, ...
Authors:Capodagli, G.C, Neiditch, M.B.
Deposit date:2017-06-06
Release date:2018-12-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA.
MBio, 9, 2018
6P9L
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BU of 6p9l by Molmil
Crystal structure of Mycobacterium tuberculosis KasA in complex with JFX
Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 1, 4-fluoro-N-(3-methyl-1H-indazol-5-yl)butane-1-sulfonamide, GLYCEROL, ...
Authors:Capodagli, G.C, Neiditch, M.B.
Deposit date:2019-06-10
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.305 Å)
Cite:A Preclinical Candidate Targeting Mycobacterium tuberculosis KasA.
Cell Chem Biol, 27, 2020
6P9K
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BU of 6p9k by Molmil
Crystal structure of Mycobacterium tuberculosis KasA in complex with O6G
Descriptor: 3-oxoacyl-ACP synthase, GLYCEROL, ISOPROPYL ALCOHOL, ...
Authors:Capodagli, G.C, Neiditch, M.B.
Deposit date:2019-06-10
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.703 Å)
Cite:A Preclinical Candidate Targeting Mycobacterium tuberculosis KasA.
Cell Chem Biol, 27, 2020
6P9M
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BU of 6p9m by Molmil
Crystal structure of Mycobacterium tuberculosis KasA in complex with O6J
Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 1, GLYCEROL, ISOPROPYL ALCOHOL, ...
Authors:Capodagli, G.C, Neiditch, M.B.
Deposit date:2019-06-10
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.256 Å)
Cite:A Preclinical Candidate Targeting Mycobacterium tuberculosis KasA.
Cell Chem Biol, 27, 2020
6GRZ
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BU of 6grz by Molmil
Crystal structure of the light chain dimer mH6
Descriptor: GLYCEROL, mH6
Authors:Maritan, M, Ricagno, S, Ambrosetti, A, Oberti, L.
Deposit date:2018-06-13
Release date:2019-06-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Inherent Biophysical Properties Modulate the Toxicity of Soluble Amyloidogenic Light Chains
J.Mol.Biol., 2020
5OLF
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BU of 5olf by Molmil
Ligand-Based NMR Study of C-X-C Chemokine Receptor Type 4 (CXCR4)-Ligand Interactions in Living Cancer Cells
Descriptor: GBA-ALA-CYS-ARG-PHE-PHE-CYS
Authors:Brancaccio, D, Carotenuto, A.
Deposit date:2017-07-27
Release date:2018-06-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Ligand-Based NMR Study of C-X-C Chemokine Receptor Type 4 (CXCR4)-Ligand Interactions on Living Cancer Cells.
J. Med. Chem., 61, 2018
2JSP
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BU of 2jsp by Molmil
The prokaryotic Cys2His2 zinc finger adopts a novel fold as revealed by the NMR structure of A. tumefaciens Ros DNA binding domain
Descriptor: Transcriptional regulatory protein ros
Authors:Malgieri, G.
Deposit date:2007-07-10
Release date:2007-10-16
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:The prokaryotic Cys2His2 zinc-finger adopts a novel fold as revealed by the NMR structure of Agrobacterium tumefaciens Ros DNA-binding domain.
Proc.Natl.Acad.Sci.Usa, 104, 2007
6POR
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BU of 6por by Molmil
Antimicrobial lasso peptide ubonodin
Descriptor: Ubonodin
Authors:Link, A.J, Cheung-Lee, W.L.
Deposit date:2019-07-05
Release date:2019-12-04
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Discovery of Ubonodin, an Antimicrobial Lasso Peptide Active against Members of the Burkholderia cepacia Complex.
Chembiochem, 21, 2020
5M6A
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BU of 5m6a by Molmil
Crystal structure of cardiotoxic Bence-Jones light chain dimer H9
Descriptor: Bence-Jones light chain, GLYCEROL, PHOSPHATE ION
Authors:Oberti, L, Rognoni, P, Bacarizo, J, Bolognesi, M, Ricagno, S.
Deposit date:2016-10-24
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017

 

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