6P9K

Crystal structure of Mycobacterium tuberculosis KasA in complex with O6G

Summary for 6P9K

Entry DOI	10.2210/pdb6p9k/pdb
Related	5W2O 5W2P 5W2Q 5W2S
Descriptor	3-oxoacyl-ACP synthase, SODIUM ION, ISOPROPYL ALCOHOL, ... (6 entities in total)
Functional Keywords	beta ketoacyl synthase i, lipid synthesis, fatty acid biosynthesis, transferase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	43848.64
Authors	Capodagli, G.C.,Neiditch, M.B. (deposition date: 2019-06-10, release date: 2020-04-01, Last modification date: 2023-10-11)
Primary citation	Inoyama, D.,Awasthi, D.,Capodagli, G.C.,Tsotetsi, K.,Sukheja, P.,Zimmerman, M.,Li, S.G.,Jadhav, R.,Russo, R.,Wang, X.,Grady, C.,Richmann, T.,Shrestha, R.,Li, L.,Ahn, Y.M.,Ho Liang, H.P.,Mina, M.,Park, S.,Perlin, D.S.,Connell, N.,Dartois, V.,Alland, D.,Neiditch, M.B.,Kumar, P.,Freundlich, J.S. A Preclinical Candidate Targeting Mycobacterium tuberculosis KasA. Cell Chem Biol, 27:560-, 2020 Cited by PubMed: 32197094 DOI: 10.1016/j.chembiol.2020.02.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.703 Å)

Structure validation