5M6A
Crystal structure of cardiotoxic Bence-Jones light chain dimer H9
Summary for 5M6A
| Entry DOI | 10.2210/pdb5m6a/pdb |
| Descriptor | Bence-Jones light chain, GLYCEROL, PHOSPHATE ION, ... (4 entities in total) |
| Functional Keywords | light chain dimer, light chain amyloidosis, immunoglobulin fold, protein aggregation, immune system |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 4 |
| Total formula weight | 90851.92 |
| Authors | Oberti, L.,Rognoni, P.,Bacarizo, J.,Bolognesi, M.,Ricagno, S. (deposition date: 2016-10-24, release date: 2017-11-15, Last modification date: 2024-01-17) |
| Primary citation | Oberti, L.,Rognoni, P.,Barbiroli, A.,Lavatelli, F.,Russo, R.,Maritan, M.,Palladini, G.,Bolognesi, M.,Merlini, G.,Ricagno, S. Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity. Sci Rep, 7:16809-16809, 2017 Cited by PubMed: 29196671DOI: 10.1038/s41598-017-16953-7 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.64 Å) |
Structure validation
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