6P9M

Crystal structure of Mycobacterium tuberculosis KasA in complex with O6J

Summary for 6P9M

Entry DOI	10.2210/pdb6p9m/pdb
Descriptor	3-oxoacyl-[acyl-carrier-protein] synthase 1, SODIUM ION, N-(2-cyano-3-methyl-1H-indol-5-yl)pentane-1-sulfonamide, ... (6 entities in total)
Functional Keywords	beta ketoacyl synthase i, lipid synthesis, fatty acid biosynthesis, transferase
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Total number of polymer chains	1
Total formula weight	43834.57
Authors	Capodagli, G.C.,Neiditch, M.B. (deposition date: 2019-06-10, release date: 2020-04-01, Last modification date: 2023-10-11)
Primary citation	Inoyama, D.,Awasthi, D.,Capodagli, G.C.,Tsotetsi, K.,Sukheja, P.,Zimmerman, M.,Li, S.G.,Jadhav, R.,Russo, R.,Wang, X.,Grady, C.,Richmann, T.,Shrestha, R.,Li, L.,Ahn, Y.M.,Ho Liang, H.P.,Mina, M.,Park, S.,Perlin, D.S.,Connell, N.,Dartois, V.,Alland, D.,Neiditch, M.B.,Kumar, P.,Freundlich, J.S. A Preclinical Candidate Targeting Mycobacterium tuberculosis KasA. Cell Chem Biol, 27:560-, 2020 Cited by PubMed: 32197094 DOI: 10.1016/j.chembiol.2020.02.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.256 Å)

Structure validation