7NDG
| Cryo-EM structure of the ternary complex between Netrin-1, Neogenin and Repulsive Guidance Molecule B | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neogenin, ... | 著者 | Robinson, R.A, Griffiths, S.C, van de Haar, L.L, Malinauskas, T, van Battum, E.Y, Zelina, P, Schwab, R.A, Karia, D, Malinauskaite, L, Brignani, S, van den Munkhof, M, Dudukcu, O, De Ruiter, A.A, Van den Heuvel, D.M.A, Bishop, B, Elegheert, J, Aricescu, A.R, Pasterkamp, R.J, Siebold, C. | 登録日 | 2021-02-01 | 公開日 | 2021-03-31 | 最終更新日 | 2021-04-28 | 実験手法 | ELECTRON MICROSCOPY (5.98 Å) | 主引用文献 | Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling. Cell, 184, 2021
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7NE0
| Structure of the ternary complex between Netrin-1, Repulsive-Guidance Molecule-B (RGMB) and Neogenin | 分子名称: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Robinson, R.A, Griffiths, S.C, van de Haar, L.L, Malinauskas, T, van Battum, E.Y, Zelina, P, Schwab, R.A, Karia, D, Malinauskaite, L, Brignani, S, van den Munkhof, M, Dudukcu, O, De Ruiter, A.A, Van den Heuvel, D.M.A, Bishop, B, Elegheert, J, Aricescu, A.R, Pasterkamp, R.J, Siebold, C. | 登録日 | 2021-02-02 | 公開日 | 2021-03-31 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling. Cell, 184, 2021
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7NE1
| Structure of the complex between Netrin-1 and its receptor Neogenin | 分子名称: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Robinson, R.A, Griffiths, S.C, van de Haar, L.L, Malinauskas, T, van Battum, E.Y, Zelina, P, Schwab, R.A, Karia, D, Malinauskaite, L, Brignani, S, van den Munkhof, M, Dudukcu, O, De Ruiter, A.A, Van den Heuvel, D.M.A, Bishop, B, Elegheert, J, Aricescu, A.R, Pasterkamp, R.J, Siebold, C. | 登録日 | 2021-02-02 | 公開日 | 2021-03-31 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling. Cell, 184, 2021
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2VGE
| Crystal structure of the C-terminal region of human iASPP | 分子名称: | RELA-ASSOCIATED INHIBITOR | 著者 | Robinson, R.A, Lu, X, Jones, E.Y, Siebold, C. | 登録日 | 2007-11-12 | 公開日 | 2008-02-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Biochemical and Structural Studies of Aspp Proteins Reveal Differential Binding to P53, P63 and P73 Structure, 16, 2008
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6QP7
| Drosophila Semaphorin 2a | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Robinson, R.A, Rozbesky, D, Harlos, K, Siebold, C, Jones, E.Y. | 登録日 | 2019-02-13 | 公開日 | 2019-08-21 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning. Nat Commun, 10, 2019
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6QP8
| Drosophila Semaphorin 2b | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, ... | 著者 | Robinson, R.A, Rozbesky, D, Harlos, K, Siebold, C, Jones, E.Y. | 登録日 | 2019-02-13 | 公開日 | 2019-08-21 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning. Nat Commun, 10, 2019
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7ZT8
| Structure of E8 TCR in complex in human MR1 bound to 3FBA | 分子名称: | 1,2-ETHANEDIOL, 3-methylbenzoic acid, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ... | 著者 | Karuppiah, V, Srikannathasan, V, Robinson, R.A. | 登録日 | 2022-05-09 | 公開日 | 2023-06-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023
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7ZT3
| Structure of E8 TCR in complex in human MR1 K43A | 分子名称: | Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, TCR alpha, ... | 著者 | Karuppiah, V, Srikannathasan, V, Robinson, R.A. | 登録日 | 2022-05-09 | 公開日 | 2023-06-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023
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7ZT2
| Structure of E8 TCR in complex with human MR1 bound to 5-OP-RU | 分子名称: | 1,2-ETHANEDIOL, 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, ... | 著者 | Karuppiah, V, Srikannathasan, V, Robinson, R.A. | 登録日 | 2022-05-09 | 公開日 | 2023-06-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023
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7ZT4
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7ZT5
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7ZT9
| Structure of E8 TCR in complex in human MR1 bound to 4FBA | 分子名称: | 1,2-ETHANEDIOL, 4-METHYLBENZOIC ACID, Beta-2-microglobulin, ... | 著者 | Karuppiah, V, Srikannathasan, V, Robinson, R.A. | 登録日 | 2022-05-09 | 公開日 | 2023-06-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023
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7ZT7
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6QP9
| Drosophila Semaphorin 1a, extracellular domains 1-2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Semaphorin-1A | 著者 | Rozbesky, D, Robinson, R.A, Harlos, K, Siebold, C, Jones, E.Y. | 登録日 | 2019-02-13 | 公開日 | 2019-08-21 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning. Nat Commun, 10, 2019
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6RSY
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6ZKX
| Crystal structure of InhA:01 TCR in complex with HLA-E (Y84C) bound to InhA (53-61 GCG) | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], ... | 著者 | Srikannathasan, V, Karuppiah, V, Robinson, R.A. | 登録日 | 2020-06-30 | 公開日 | 2022-01-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur.J.Immunol., 52, 2022
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6ZKY
| Crystal structure of InhA:01 TCR in complex with HLA-E (S147C) bound to InhA (53-61 H3C) | 分子名称: | Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], HLA class I histocompatibility antigen, ... | 著者 | Srikannathasan, V, Karuppiah, V, Robinson, R.A. | 登録日 | 2020-06-30 | 公開日 | 2022-01-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur.J.Immunol., 52, 2022
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6ZKZ
| Crystal structure of InhA:01 TCR in complex with HLA-E (F116C) bound to InhA (53-61 H4C) | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], ... | 著者 | Srikannathasan, V, Karuppiah, V, Robinson, R.A. | 登録日 | 2020-06-30 | 公開日 | 2022-01-26 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur.J.Immunol., 52, 2022
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6ZKW
| Crystal structure of InhA:01 TCR in complex with HLA-E bound to InhA (53-61) | 分子名称: | Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], HLA class I histocompatibility antigen, ... | 著者 | Srikannathasan, V, Karuppiah, V, Robinson, R.A. | 登録日 | 2020-06-30 | 公開日 | 2022-01-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur.J.Immunol., 52, 2022
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7NDU
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7NDT
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7NDQ
| Gag:02 TCR in complex with HLA-E. | 分子名称: | Beta-2-microglobulin, Gag6V, HLA class I histocompatibility antigen, ... | 著者 | Pengelly, R.J, Robinson, R.A. | 登録日 | 2021-02-02 | 公開日 | 2022-01-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.551 Å) | 主引用文献 | Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur.J.Immunol., 52, 2022
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3OKT
| Mouse Plexin A2, extracellular domains 1-4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | 著者 | Janssen, B.J.C, Robinson, R.A, Bell, C.H, Siebold, C, Jones, E.Y. | 登録日 | 2010-08-25 | 公開日 | 2010-10-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.296 Å) | 主引用文献 | Structural basis of semaphorin-plexin signalling. Nature, 467, 2010
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3OKW
| Mouse Semaphorin 6A, extracellular domains 1-2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ... | 著者 | Janssen, B.J.C, Robinson, R.A, Bell, C.H, Siebold, C, Jones, E.Y. | 登録日 | 2010-08-25 | 公開日 | 2010-10-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | 主引用文献 | Structural basis of semaphorin-plexin signalling. Nature, 467, 2010
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3OL2
| Receptor-ligand structure of Human Semaphorin 4D with Plexin B1. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-B1, ... | 著者 | Janssen, B.J.C, Robinson, R.A, Perez-Branguli, F, Bell, C.H, Mitchell, C.J, Siebold, C, Jones, E.Y. | 登録日 | 2010-08-25 | 公開日 | 2010-10-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Structural basis of semaphorin-plexin signalling. Nature, 467, 2010
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