6ZKW

Crystal structure of InhA:01 TCR in complex with HLA-E bound to InhA (53-61)

Summary for 6ZKW

Entry DOI	10.2210/pdb6zkw/pdb
Descriptor	HLA class I histocompatibility antigen, alpha chain E, Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], ... (6 entities in total)
Functional Keywords	t cell receptor, tcr, hla-e, inha, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	5
Total formula weight	93671.85
Authors	Srikannathasan, V.,Karuppiah, V.,Robinson, R.A. (deposition date: 2020-06-30, release date: 2022-01-26, Last modification date: 2024-01-31)
Primary citation	Barber, C.,De Souza, V.A.,Paterson, R.L.,Martin-Urdiroz, M.,Mulakkal, N.C.,Srikannathasan, V.,Connolly, M.,Phillips, G.,Foong-Leong, T.,Pengelly, R.,Karuppiah, V.,Grant, T.,Dembek, M.,Verma, A.,Gibbs-Howe, D.,Blicher, T.H.,Knox, A.,Robinson, R.A.,Cole, D.K.,Leonard, S. Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur.J.Immunol., 52:618-632, 2022 Cited by PubMed: 35108401 DOI: 10.1002/eji.202149745 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.26 Å)

Structure validation