7ZT3

Structure of E8 TCR in complex in human MR1 K43A

Summary for 7ZT3

Entry DOI	10.2210/pdb7zt3/pdb
Descriptor	Major histocompatibility complex class I-related gene protein, Beta-2-microglobulin, TCR alpha, ... (5 entities in total)
Functional Keywords	mr1, tcr, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	97731.80
Authors	Karuppiah, V.,Srikannathasan, V.,Robinson, R.A. (deposition date: 2022-05-09, release date: 2023-06-28, Last modification date: 2024-02-07)
Primary citation	Chancellor, A.,Alan Simmons, R.,Khanolkar, R.C.,Nosi, V.,Beshirova, A.,Berloffa, G.,Colombo, R.,Karuppiah, V.,Pentier, J.M.,Tubb, V.,Ghadbane, H.,Suckling, R.J.,Page, K.,Crean, R.M.,Vacchini, A.,De Gregorio, C.,Schaefer, V.,Constantin, D.,Gligoris, T.,Lloyd, A.,Hock, M.,Srikannathasan, V.,Robinson, R.A.,Besra, G.S.,van der Kamp, M.W.,Mori, L.,Calogero, R.,Cole, D.K.,De Libero, G.,Lepore, M. Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220:-, 2023 Cited by PubMed: 37382893 DOI: 10.1084/jem.20221939 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation