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1XDK
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BU of 1xdk by Molmil
Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator
分子名称: (9cis)-retinoic acid, Retinoic acid receptor RXR-alpha, Retinoic acid receptor, ...
著者Pogenberg, V, Guichou, J.F, Vivat-Hannah, V, Kammerer, S, Perez, E, Germain, P, De Lera, A.R, Gronemeyer, H, Royer, C.A, Bourguet, W.
登録日2004-09-07
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献CHARACTERIZATION OF THE INTERACTION BETWEEN RAR/RXR HETERODIMERS AND TRANSCRIPTIONAL COACTIVATORS THROUGH STRUCTURAL AND FLUORESCENCE ANISOTROPY STUDIES
J.Biol.Chem., 280, 2005
6FX5
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BU of 6fx5 by Molmil
MITF dimerization mutant
分子名称: Microphthalmia-associated transcription factor, SULFATE ION
著者Pogenberg, V, Milewski, M, Wilmanns, M.
登録日2018-03-08
公開日2019-03-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Mechanism of conditional partner selectivity in MITF/TFE family transcription factors with a conserved coiled coil stammer motif.
Nucleic Acids Res., 48, 2020
4ATK
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BU of 4atk by Molmil
MITF:E-box complex
分子名称: 5'-D(*AP*GP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*CP*T)-3', MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR
著者Pogenberg, V, Deineko, V, Wilmanns, M.
登録日2012-05-08
公開日2012-12-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Restricted Leucine Zipper Dimerization and Specificity of DNA Recognition of the Melanocyte Master Regulator Mitf
Genes Dev., 26, 2012
4ATI
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BU of 4ati by Molmil
MITF:M-box complex
分子名称: 5'-D(*AP*GP*GP*GP*TP*CP*AP*TP*GP*TP*GP*CP*TP*AP*AP*C)-3', 5'-D(*GP*TP*TP*AP*GP*CP*AP*CP*AP*TP*GP*AP*CP*CP*CP*T)-3', MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR
著者Pogenberg, V, Deineko, V, Wilmanns, M.
登録日2012-05-08
公開日2012-12-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Restricted Leucine Zipper Dimerization and Specificity of DNA Recognition of the Melanocyte Master Regulator Mitf
Genes Dev., 26, 2012
4ATH
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BU of 4ath by Molmil
MITF apo structure
分子名称: MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR, SULFATE ION
著者Pogenberg, V, Milewski, M, Wilmanns, M.
登録日2012-05-08
公開日2012-12-12
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Restricted Leucine Zipper Dimerization and Specificity of DNA Recognition of the Melanocyte Master Regulator Mitf
Genes Dev., 26, 2012
2WT7
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BU of 2wt7 by Molmil
Crystal structure of the bZIP heterodimeric complex MafB:cFos bound to DNA
分子名称: MODIFIED T-MARE MOTIF, PHOSPHATE ION, PROTO-ONCOGENE PROTEIN C-FOS, ...
著者Pogenberg, V, Holton, S, Wilmanns, M.
登録日2009-09-11
公開日2010-09-29
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Design of a bZIP Transcription Factor with Homo/Heterodimer-Induced DNA-Binding Preference.
Structure, 22, 2014
6G1L
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BU of 6g1l by Molmil
MITF/CLEARbox structure
分子名称: CLEAR-box, Microphthalmia-associated transcription factor
著者Pogenberg, V, Wilmanns, M.
登録日2018-03-21
公開日2019-02-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献MITF has a central role in regulating starvation-induced autophagy in melanoma.
Sci Rep, 9, 2019
2XIV
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BU of 2xiv by Molmil
Structure of Rv1477, hypothetical invasion protein of Mycobacterium tuberculosis
分子名称: GLYCEROL, HYPOTHETICAL INVASION PROTEIN
著者Pogenberg, V, Tizzano, B, Wilmanns, M.
登録日2010-07-01
公開日2010-07-14
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of Rv1477, Hypothetical Invasion Protein of Mycobacterium Tuberculosis
To be Published
3L1P
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BU of 3l1p by Molmil
POU protein:DNA complex
分子名称: DNA (5'-D(*AP*TP*CP*CP*AP*TP*TP*TP*GP*CP*CP*TP*TP*TP*CP*AP*AP*AP*TP*GP*TP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*AP*CP*AP*TP*TP*TP*GP*AP*AP*AP*GP*GP*CP*AP*AP*AP*TP*GP*GP*A)-3'), POU domain, ...
著者Vahokoski, J, Groves, M.R, Pogenberg, V, Wilmanns, M.
登録日2009-12-14
公開日2010-12-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A unique Oct4 interface is crucial for reprogramming to pluripotency
Nat.Cell Biol., 15, 2013
6HT5
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BU of 6ht5 by Molmil
Oct4/Sox2:UTF1 structure
分子名称: DNA (5'-D(*TP*TP*CP*AP*CP*TP*AP*GP*CP*AP*TP*AP*AP*CP*AP*AP*TP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*CP*AP*TP*TP*GP*TP*TP*AP*TP*GP*CP*TP*AP*GP*TP*GP*AP*AP*G)-3'), POU domain, ...
著者Vahokoski, J, Meusch, D, Groves, M, Pogenberg, V, Wilmanns, M.
登録日2018-10-03
公開日2019-10-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.451 Å)
主引用文献Oct4/Sox2:UTF1 structure
To Be Published
6ZMD
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BU of 6zmd by Molmil
Crystal structure of HYPE covalently tethered to BiP bound to AMP-PNP
分子名称: Endoplasmic reticulum chaperone BiP, MAGNESIUM ION, PHOSPHATE ION, ...
著者Fauser, J, Gulen, B, Pett, C, Hedberg, C, Itzen, A, Pogenberg, V.
登録日2020-07-02
公開日2021-04-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD.
Nat Commun, 12, 2021
8AGG
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BU of 8agg by Molmil
Structure of the Legionella phosphocholine hydrolase Lem3
分子名称: MAGNESIUM ION, Phosphocholine hydrolase Lem3
著者Kaspers, M.S, Itzen, A, Pogenberg, V.
登録日2022-07-20
公開日2023-04-12
最終更新日2023-05-03
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Dephosphocholination by Legionella effector Lem3 functions through remodelling of the switch II region of Rab1b.
Nat Commun, 14, 2023
6SIU
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BU of 6siu by Molmil
Crystal structure of IbpAFic2 covalently tethered to Cdc42
分子名称: Cell division control protein 42 homolog, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
著者Gulen, B, Roselin, M, Albers, M, Hedberg, C, Itzen, A, Pogenberg, V.
登録日2019-08-12
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Identification of targets of AMPylating Fic enzymes by co-substrate-mediated covalent capture.
Nat.Chem., 12, 2020
8ANP
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BU of 8anp by Molmil
Legionella effector Lem3 mutant D190A in complex with Mg2+
分子名称: MAGNESIUM ION, Phosphocholine hydrolase Lem3, SULFATE ION, ...
著者Kaspers, M.S, Pogenberg, V, Ernst, S, Ecker, F, Pett, C, Ochtrop, P, Hedberg, C, Groll, M, Itzen, A.
登録日2022-08-05
公開日2023-04-12
最終更新日2023-05-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dephosphocholination by Legionella effector Lem3 functions through remodelling of the switch II region of Rab1b.
Nat Commun, 14, 2023
8ALK
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BU of 8alk by Molmil
Structure of the Legionella phosphocholine hydrolase Lem3 in complex with its substrate Rab1
分子名称: 2-[[[5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxyethyl-[3-(2-chloranylethanoylamino)propyl]-dimethyl-azanium, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
著者Kaspers, M.S, Pett, C, Hedberg, C, Itzen, A, Pogenberg, V.
登録日2022-08-01
公開日2023-04-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Dephosphocholination by Legionella effector Lem3 functions through remodelling of the switch II region of Rab1b.
Nat Commun, 14, 2023
8CIL
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BU of 8cil by Molmil
Crystal structure of Coxiella burnetii Fic protein 2
分子名称: Fic family protein
著者Hoepfner, D, Itzen, A, Pogenberg, V.
登録日2023-02-10
公開日2023-11-15
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献The DNA-binding induced (de)AMPylation activity of a Coxiella burnetii Fic enzyme targets Histone H3.
Commun Biol, 6, 2023
6FKG
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BU of 6fkg by Molmil
Crystal structure of the M.tuberculosis MbcT-MbcA toxin-antitoxin complex.
分子名称: GLYCEROL, Rv1989c (MbcT), Rv1990c (MbcA)
著者Freire, D.M, Cianci, M, Pogenberg, V, Schneider, T.R, Wilmanns, M, Parret, A.H.A.
登録日2018-01-24
公開日2019-02-27
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献An NAD+Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.
Mol.Cell, 73, 2019
3ZMQ
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BU of 3zmq by Molmil
Src-derived mutant peptide inhibitor complex of PTP1B
分子名称: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1
著者Temmerman, K, Pogenberg, V, Meyer, C, Koehn, M, Wilmanns, M.
登録日2013-02-12
公開日2014-01-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Development of Accessible Peptidic Tool Compounds to Study the Phosphatase Ptp1B in Intact Cells.
Acs Chem.Biol., 9, 2014
3ZMP
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BU of 3zmp by Molmil
Src-derived peptide inhibitor complex of PTP1B
分子名称: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1
著者Temmerman, K, Pogenberg, V, Meyer, C, Koehn, M, Wilmanns, M.
登録日2013-02-12
公開日2014-01-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.619 Å)
主引用文献Development of Accessible Peptidic Tool Compounds to Study the Phosphatase Ptp1B in Intact Cells.
Acs Chem.Biol., 9, 2014
4B4L
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BU of 4b4l by Molmil
CRYSTAL STRUCTURE OF AN ARD DAP-KINASE 1 MUTANT
分子名称: DEATH-ASSOCIATED PROTEIN KINASE 1, PENTAETHYLENE GLYCOL, SULFATE ION
著者Temmerman, K, Pogenberg, V, Jonko, W, Wilmanns, M.
登録日2012-07-31
公開日2013-08-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A Pef/Y Substrate Recognition and Signature Motif Plays a Critical Role in Dapk-Related Kinase Activity.
Chem.Biol., 21, 2014
4CHG
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BU of 4chg by Molmil
Crystal structure of VapBC15 complex from Mycobacterium tuberculosis
分子名称: ANTITOXIN VAPB15, MAGNESIUM ION, MANGANESE (II) ION, ...
著者Das, U, Pogenberg, V, Tiruttani Subhramanyam, U.K, Wilmanns, M, Srinivasan, A, Gourinath, S.
登録日2013-12-02
公開日2014-11-12
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the Vapbc-15 Complex from Mycobacterium Tuberculosis Reveals a Two-Metal Ion Dependent Pin-Domain Ribonuclease And a Variable Mode of Toxin-Antitoxin Assembly.
J.Struct.Biol., 188, 2014
2WTY
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BU of 2wty by Molmil
Crystal structure of the homodimeric MafB in complex with the T-MARE binding site
分子名称: DNA (5'-D(*TP*AP*AP*TP*TP*GP*CP*TP*GP*AP*CP*TP*CP*AP *GP*CP*AP*AP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*TP*TP*GP*CP*TP*GP*AP*GP*TP*CP*AP *GP*CP*AP*AP*TP*T)-3'), MAGNESIUM ION, ...
著者Consani Textor, L, Holton, S, Wilmanns, M.
登録日2009-09-25
公開日2010-12-08
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Design of a bZIP Transcription Factor with Homo/Heterodimer-Induced DNA-Binding Preference.
Structure, 22, 2014
5AF3
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BU of 5af3 by Molmil
X-RAY CRYSTAL STRUCTURE OF RV2018 FROM MYCOBACTERIUM TUBERCULOSIS
分子名称: GLYCEROL, VAPBC49
著者Holton, S.J, Wilmanns, M.
登録日2015-01-18
公開日2016-01-27
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal Structure and DNA Binding Ability of Myco Tuberculosis Vapbc49 Anti-Toxin Protein Bacterium
To be Published
5NEW
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BU of 5new by Molmil
RNA-RNA base stacking in the crystal structure of an Hfq6:RNA dimer
分子名称: RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3'), RNA (5'-R(P*UP*U)-3'), RNA-binding protein Hfq, ...
著者Schulz, E.C, Barabas, O.
登録日2017-03-12
公開日2017-10-04
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2.511 Å)
主引用文献Intermolecular base stacking mediates RNA-RNA interaction in a crystal structure of the RNA chaperone Hfq.
Sci Rep, 7, 2017
3MZH
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BU of 3mzh by Molmil
Crystal structure of cAMP receptor protein from mycobacterium tuberculosis in complex with cAMP and its DNA binding element
分子名称: 5'-D(P*AP*AP*AP*TP*GP*TP*GP*AP*TP*CP*TP*AP*GP*GP*TP*CP*AP*CP*GP*TP*G)-3', 5'-D(P*CP*AP*CP*GP*TP*GP*AP*CP*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*C)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ...
著者Akhter, Y, Wilmanns, M.
登録日2010-05-12
公開日2011-06-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure of Camp Receptor Protein from Mycobacterium Tuberculosis in Complex with DNA and cAMP
To be Published

 

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