1XDK
Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator
Summary for 1XDK
Entry DOI | 10.2210/pdb1xdk/pdb |
Related | 1DKF |
Descriptor | Retinoic acid receptor RXR-alpha, Retinoic acid receptor, beta, Thyroid Receptor Associated Protein 220, ... (5 entities in total) |
Functional Keywords | nuclear receptor, coactivator, ligand, hormone-growth factor receptor complex, hormone/growth factor receptor |
Biological source | Mus musculus (house mouse) More |
Cellular location | Nucleus: P28700 P22605 |
Total number of polymer chains | 8 |
Total formula weight | 128757.06 |
Authors | Pogenberg, V.,Guichou, J.F.,Vivat-Hannah, V.,Kammerer, S.,Perez, E.,Germain, P.,De Lera, A.R.,Gronemeyer, H.,Royer, C.A.,Bourguet, W. (deposition date: 2004-09-07, release date: 2004-11-09, Last modification date: 2023-08-23) |
Primary citation | Pogenberg, V.,Guichou, J.F.,Vivat-Hannah, V.,Kammerer, S.,Perez, E.,Germain, P.,De Lera, A.R.,Gronemeyer, H.,Royer, C.A.,Bourguet, W. CHARACTERIZATION OF THE INTERACTION BETWEEN RAR/RXR HETERODIMERS AND TRANSCRIPTIONAL COACTIVATORS THROUGH STRUCTURAL AND FLUORESCENCE ANISOTROPY STUDIES J.Biol.Chem., 280:1625-1633, 2005 Cited by PubMed: 15528208DOI: 10.1074/jbc.M409302200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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