6FKG

Crystal structure of the M.tuberculosis MbcT-MbcA toxin-antitoxin complex.

Summary for 6FKG

Entry DOI	10.2210/pdb6fkg/pdb
Descriptor	Rv1989c (MbcT), Rv1990c (MbcA), GLYCEROL, ... (4 entities in total)
Functional Keywords	toxin-antitoxin system phosphorylase nad+-binding, toxin
Biological source	Mycobacterium tuberculosis More
Total number of polymer chains	4
Total formula weight	66070.38
Authors	Freire, D.M.,Cianci, M.,Pogenberg, V.,Schneider, T.R.,Wilmanns, M.,Parret, A.H.A. (deposition date: 2018-01-24, release date: 2019-02-27, Last modification date: 2019-04-03)
Primary citation	Freire, D.M.,Gutierrez, C.,Garza-Garcia, A.,Grabowska, A.D.,Sala, A.J.,Ariyachaokun, K.,Panikova, T.,Beckham, K.S.H.,Colom, A.,Pogenberg, V.,Cianci, M.,Tuukkanen, A.,Boudehen, Y.M.,Peixoto, A.,Botella, L.,Svergun, D.I.,Schnappinger, D.,Schneider, T.R.,Genevaux, P.,de Carvalho, L.P.S.,Wilmanns, M.,Parret, A.H.A.,Neyrolles, O. An NAD+Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death. Mol.Cell, 73:1282-1291.e8, 2019 Cited by PubMed: 30792174 DOI: 10.1016/j.molcel.2019.01.028 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation