3L1P

POU protein:DNA complex

Summary for 3L1P

DescriptorPOU domain, class 5, transcription factor 1, DNA (5'-D(*TP*CP*CP*AP*CP*AP*TP*TP*TP*GP*AP*AP*AP*GP*GP*CP*AP*AP*AP*TP*GP*GP*A)-3'), DNA (5'-D(*AP*TP*CP*CP*AP*TP*TP*TP*GP*CP*CP*TP*TP*TP*CP*AP*AP*AP*TP*GP*TP*GP*G)-3') (3 entities in total)
Functional Keywordspou, transcription factor dna complex, pore, stem cells, embryonic, transcription-dna complex, transcription/dna
Biological sourceMus musculus (mouse)
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Cellular locationCytoplasm  P20263
Total number of polymer chains4
Total molecular weight50044.92
Authors
Vahokoski, J.,Groves, M.R.,Pogenberg, V.,Wilmanns, M. (deposition date: 2009-12-14, release date: 2010-12-15, Last modification date: 2018-02-07)
Primary citation
Esch, D.,Vahokoski, J.,Groves, M.R.,Pogenberg, V.,Cojocaru, V.,Vom Bruch, H.,Han, D.,Drexler, H.C.A.,Arauzo-Bravo, M.J.,Ng, C.K.L.,Jauch, R.,Wilmanns, M.,Scholer, H.R.
A unique Oct4 interface is crucial for reprogramming to pluripotency
Nat.Cell Biol., 15:295-301, 2013
PubMed: 23376973 (PDB entries with the same primary citation)
DOI: 10.1038/ncb2680
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25771.1%12.7%1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3l1p
no rotation
Molmil generated image of 3l1p
rotated about x axis by 90°
Molmil generated image of 3l1p
rotated about y axis by 90°
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