3L1P
POU protein:DNA complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PROSITE/UniProt
| site_id | PS00027 |
| Number of Residues | 24 |
| Details | HOMEOBOX_1 'Homeobox' domain signature. IAnqLgLEkdVVRVWFsNrrqkgK |
| Chain | Residue | Details |
| A | ILE126-LYS149 |
| site_id | PS00035 |
| Number of Residues | 13 |
| Details | POU_1 POU-specific (POUs) domain signature 1. KRItLGYtQaDVG |
| Chain | Residue | Details |
| A | LYS19-GLY31 |
| site_id | PS00465 |
| Number of Residues | 14 |
| Details | POU_2 POU-specific (POUs) domain signature 2. SQTTISRFEaLqLS |
| Chain | Residue | Details |
| A | SER43-SER56 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 118 |
| Details | DNA_BIND: Homeobox => ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:23376973 |
| Chain | Residue | Details |
| A | ARG93-SER152 | |
| B | ARG93-SER152 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23376973, ECO:0007744|PDB:3L1P |
| Chain | Residue | Details |
| A | ARG20 | |
| A | GLN27 | |
| B | ARG20 | |
| B | GLN27 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q01860 |
| Chain | Residue | Details |
| A | THR98 | |
| B | THR98 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q01860 |
| Chain | Residue | Details |
| A | SER99 | |
| A | SER152 | |
| B | SER99 | |
| B | SER152 |
