3L1P
POU protein:DNA complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PROSITE/UniProt
| site_id | PS00027 |
| Number of Residues | 24 |
| Details | HOMEOBOX_1 'Homeobox' domain signature. IAnqLgLEkdVVRVWFsNrrqkgK |
| Chain | Residue | Details |
| A | ILE126-LYS149 |
| site_id | PS00035 |
| Number of Residues | 13 |
| Details | POU_1 POU-specific (POUs) domain signature 1. KRItLGYtQaDVG |
| Chain | Residue | Details |
| A | LYS19-GLY31 |
| site_id | PS00465 |
| Number of Residues | 14 |
| Details | POU_2 POU-specific (POUs) domain signature 2. SQTTISRFEaLqLS |
| Chain | Residue | Details |
| A | SER43-SER56 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 74 |
| Details | Domain: {"description":"POU-specific","evidences":[{"source":"PROSITE-ProRule","id":"PRU00530","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Region: {"description":"DNA-binding","evidences":[{"source":"PubMed","id":"23376973","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3L1P","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23376973","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3L1P","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q01860","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q01860","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
