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8ALK

Structure of the Legionella phosphocholine hydrolase Lem3 in complex with its substrate Rab1

Summary for 8ALK
Entry DOI10.2210/pdb8alk/pdb
Related8AGG
DescriptorPhosphocholine hydrolase Lem3, Ras-related protein Rab-1B, CALCIUM ION, ... (6 entities in total)
Functional Keywordsbacterial effector, dephosphocholinase, legionella pneumophila, hydrolase
Biological sourceLegionella pneumophila
More
Total number of polymer chains2
Total formula weight73838.37
Authors
Kaspers, M.S.,Pett, C.,Hedberg, C.,Itzen, A.,Pogenberg, V. (deposition date: 2022-08-01, release date: 2023-04-12, Last modification date: 2024-02-07)
Primary citationKaspers, M.S.,Pogenberg, V.,Pett, C.,Ernst, S.,Ecker, F.,Ochtrop, P.,Groll, M.,Hedberg, C.,Itzen, A.
Dephosphocholination by Legionella effector Lem3 functions through remodelling of the switch II region of Rab1b.
Nat Commun, 14:2245-2245, 2023
Cited by
PubMed: 37076474
DOI: 10.1038/s41467-023-37621-7
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.15 Å)
Structure validation

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