6G1L
MITF/CLEARbox structure
Summary for 6G1L
Entry DOI | 10.2210/pdb6g1l/pdb |
Descriptor | Microphthalmia-associated transcription factor, CLEAR-box (3 entities in total) |
Functional Keywords | melanocyte, autophagy, transcription factor, dna binding, transcription |
Biological source | Mus musculus (House Mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 19249.76 |
Authors | Pogenberg, V.,Wilmanns, M. (deposition date: 2018-03-21, release date: 2019-02-06, Last modification date: 2024-01-17) |
Primary citation | Moller, K.,Sigurbjornsdottir, S.,Arnthorsson, A.O.,Pogenberg, V.,Dilshat, R.,Fock, V.,Brynjolfsdottir, S.H.,Bindesboll, C.,Bessadottir, M.,Ogmundsdottir, H.M.,Simonsen, A.,Larue, L.,Wilmanns, M.,Thorsson, V.,Steingrimsson, E.,Ogmundsdottir, M.H. MITF has a central role in regulating starvation-induced autophagy in melanoma. Sci Rep, 9:1055-1055, 2019 Cited by PubMed: 30705290DOI: 10.1038/s41598-018-37522-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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